Schneider René, Persson Staffan
Max-Planck-Institute for Molecular Plant Physiology , Potsdam-Golm, Germany.
ARC Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne , Parkville, VIC, Australia.
Front Plant Sci. 2015 Jun 2;6:415. doi: 10.3389/fpls.2015.00415. eCollection 2015.
The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape, and morphogenesis. Pharmaceutical and genetic studies have provided indications for interdependent cross-talk between the cytoskeletal components. Recent live-cell imaging studies have cemented this notion, in particular when the cytoskeleton rearranges. However, the proteins that directly mediate this cross-talk have remained largely elusive. Recent data indicate that certain proteins can interact with both cytoskeletal arrays at the same time, and hence connecting them. In this review, we summarize the recent literature of the AF- and MT-interactors, mainly focusing on a plant-specific mediator of cytoskeletal cross-talk: the calponin homology (CH) domain-containing kinesin-14 motor proteins (KCHs).
植物细胞的细胞骨架由肌动蛋白丝(AFs)和微管(MTs)组成,是各种细胞内过程的核心结构,如细胞分裂、各向同性和极性生长、囊泡运输、细胞形状和形态发生。药物和遗传学研究表明细胞骨架成分之间存在相互依赖的相互作用。最近的活细胞成像研究巩固了这一观点,特别是当细胞骨架重新排列时。然而,直接介导这种相互作用的蛋白质在很大程度上仍然难以捉摸。最近的数据表明,某些蛋白质可以同时与两种细胞骨架阵列相互作用,从而将它们连接起来。在这篇综述中,我们总结了AF和MT相互作用蛋白的最新文献,主要关注细胞骨架相互作用的植物特异性介质:含钙调蛋白同源(CH)结构域的驱动蛋白-14运动蛋白(KCHs)。