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台湾鹅细小病毒衣壳基因VP2中自然重组的证据。

Evidence for natural recombination in the capsid gene VP2 of Taiwanese goose parvovirus.

作者信息

Wang Shao, Cheng Xiaoxia, Chen Shaoying, Lin Fengqiang, Chen Shilong, Zhu Xiaoli, Wang Jingxiang

机构信息

Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agriculture Sciences, 247 Wusi Road, Fuzhou, 350003, Fujian, People's Republic of China.

出版信息

Arch Virol. 2015 Aug;160(8):2111-5. doi: 10.1007/s00705-015-2491-2. Epub 2015 Jun 18.

Abstract

To investigate the possible role of recombination in the evolution of Muscovy duck parvovirus (MDPV) and goose parvovirus (GPV) in Taiwan, we analyzed a potentially significant recombination event that occurred only in GPV by comparing thirteen complete sequences of the capsid gene VP2 of GPV and MDPV. The recombination event occurred between GPV strain 06-0239 as the minor parent and strains 99-0808 as the major parent, which resulted in the GPV recombinant V325/TW03. GPV V325/TW03 is likely to represent a new genotype among the Taiwanese GPV strains. This represents the first evidence that intergenotype recombination within the VP2 gene cluster contributes to the genetic diversity of the VP2 genes of Taiwanese GPV field strains.

摘要

为了研究重组在台湾番鸭细小病毒(MDPV)和鹅细小病毒(GPV)进化中的可能作用,我们通过比较13条GPV和MDPV衣壳基因VP2的完整序列,分析了仅发生在GPV中的一个潜在的重要重组事件。该重组事件发生在作为次要亲本的GPV毒株06 - 0239和作为主要亲本的毒株99 - 0808之间,产生了GPV重组体V325/TW03。GPV V325/TW03可能代表台湾GPV毒株中的一个新基因型。这是首次有证据表明VP2基因簇内的基因型间重组有助于台湾GPV田间毒株VP2基因的遗传多样性。

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