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作为动物中新出现病原体的班替枝孢瓶霉:马子宫内膜炎病例报告及文献综述

Cladophialophora bantiana as an Emerging Pathogen in Animals: Case Report of Equine Endometritis and Review of the Literature.

作者信息

Rantala Merja, Attia Stella, Koukila-Kähkölä Pirkko, de Hoog Sybren, Anttila Marjukka, Katila Terttu

机构信息

Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland

Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Saarentaus, Finland.

出版信息

J Clin Microbiol. 2015 Sep;53(9):3047-53. doi: 10.1128/JCM.00728-15. Epub 2015 Jun 17.

DOI:10.1128/JCM.00728-15
PMID:26085616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4540934/
Abstract

We present an unusual equine endometritis case associated with Cladophialophora bantiana in a 15-year-old mare. The mare displayed infertility and uterine fluid accumulation with numerous black, hairy granules. Microscopically, the fluid revealed numerous septate, dark fungal hyphae and conidia in chains. Culture yielded C. bantiana (CBS 138271); the species was confirmed by internal transcribed spacer (ITS) sequencing. Treatment was unsuccessful. C. bantiana causes cerebral phaeohyphomycosis in humans, while animal cases are rare. Animal cases are reviewed.

摘要

我们报告了一例15岁母马发生的与班替枝孢瓶霉相关的罕见马子宫内膜炎病例。该母马表现为不育和子宫积液,并伴有大量黑色、有毛的颗粒。显微镜下,积液中可见大量分隔的深色真菌菌丝和链状分生孢子。培养分离出班替枝孢瓶霉(CBS 138271);通过内转录间隔区(ITS)测序确认了该菌种。治疗未成功。班替枝孢瓶霉在人类中引起脑暗色丝孢霉病,而动物病例罕见。本文对动物病例进行了综述。

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本文引用的文献

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Clin Microbiol Rev. 2014 Jul;27(3):527-42. doi: 10.1128/CMR.00093-13.
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ESCMID and ECMM joint clinical guidelines for the diagnosis and management of systemic phaeohyphomycosis: diseases caused by black fungi.ESCMID 和 ECMM 联合临床指南:系统暗色丝孢霉病的诊断和管理——由黑真菌引起的疾病。
Clin Microbiol Infect. 2014 Apr;20 Suppl 3:47-75. doi: 10.1111/1469-0691.12515.
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Mycoses. 2013 May;56(3):376-81. doi: 10.1111/myc.12033. Epub 2013 Jan 7.
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