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免疫功能正常个体因[具体真菌名称未给出]引起的脑暗色丝孢霉病:一例报告及文献简要综述。

Cerebral phaeohyphomycosis due to in an immunocompetent individual: A case report and brief review of literature.

作者信息

G Rathod Prachala, Mishra Bibhabati, Thakur Archana, S Loomba Poonam, Sharma Abha, Bajaj Ashish, Das Madhusmita, Bhasin Ashna

机构信息

Department of Microbiology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi, India.

出版信息

Curr Med Mycol. 2020 Jun;6(2):52-57. doi: 10.18502/CMM.6.2.2693.

Abstract

BACKGROUND AND PURPOSE

Fungal infections of the central nervous system (CNS) are life-threatening conditions that are frequently misdiagnosed with bacterial and viral CNS infections. Cerebral phaeohyphomycosis is a cerebral infection caused by dematiaceous fungi, especially . Very few cases of fungal CNS infection have been reported across the world. High clinical suspicion should be cast for the patients with brain abscess that do not respond to conventional antibiotic therapy.

CASE REPORT

We report a case of a 21-year-old male presenting with headache, seizures and weakness in the limbs. Radiological examination revealed multiple brain abscesses. After surgical excision and laboratory evaluation, it was found to be caused by C. bantiana. The patient's outcome was good with surgical excision and voriconazole therapy.

CONCLUSION

Brain abscess caused by is on rise, especially in immunocompromised groups. Thus, high clinical suspicion, accurate diagnosis and management are the fundamentals for good prognosis.

摘要

背景与目的

中枢神经系统(CNS)真菌感染是危及生命的疾病,常被误诊为细菌性和病毒性CNS感染。脑暗色丝孢霉病是由暗色真菌引起的脑部感染,尤其是。全球报道的真菌性CNS感染病例极少。对于常规抗生素治疗无效的脑脓肿患者,应高度怀疑真菌感染。

病例报告

我们报告一例21岁男性患者,表现为头痛、癫痫发作和肢体无力。影像学检查发现多个脑脓肿。经手术切除和实验室评估,发现是由班替枝孢霉引起的。手术切除和伏立康唑治疗后患者预后良好。

结论

由[此处原文缺失具体真菌名称]引起的脑脓肿呈上升趋势,尤其是在免疫功能低下人群中。因此,高度的临床怀疑、准确的诊断和管理是良好预后的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9f2/7888520/0994f9d99d61/cmm-6-52-g001.jpg

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