Elhadi Alaeldin, Rayis Duria A, Abdullahi Hala, Elbashir Leana M, Ali Naji I, Adam Ishag
Sudan Academy of Sciences, Khartoum, Sudan.
Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Biol Trace Elem Res. 2016 Jan;169(1):52-5. doi: 10.1007/s12011-015-0411-7. Epub 2015 Jun 20.
A case-control study was conducted in Khartoum Hospital Sudan to determine maternal and umbilical cord blood levels of zinc and copper in active labor versus elective cesarean delivery. Cases were women delivered vaginally and controls were women delivered by elective cesarean (before initiation of labor). Paired maternal and cord zinc and copper were measured using atomic absorption spectrophotometry. The two groups (52 paired maternal and cord in each arm) were well matched in their basic characteristics. In comparison with cesarean delivery, the median (interquartile range) of both maternal [87.0 (76.1-111.4) vs. 76.1 (65.2-88.3) μg/dL, P = 0.004] and cord zinc [97.8 (87.0-114.1) vs. 81.5(65.2-110.2) μg/dL P = 0.034] levels were significantly higher in the vaginal delivery. While there was no significant difference in the maternal copper [78.8 (48.1-106.1) vs. 92.4 (51.9-114.9) μg/dL, P = 0.759], the cord copper [43.5(29.9-76.1) vs. 32.2(21.7-49.6) μg/dL, P = 0.019] level was significantly higher in vaginal delivery. There was no significant correlation between zinc (both maternal and cord) and copper. While the cord zinc was significantly correlated with maternal zinc, there was no significant correlation between maternal and cord copper. The current study showed significantly higher levels of maternal and cord zinc and cord copper in women who delivered vaginally compared with caesarean delivery.
在苏丹喀土穆医院进行了一项病例对照研究，以确定顺产与择期剖宫产产妇及脐带血中锌和铜的水平。病例组为经阴道分娩的女性，对照组为择期剖宫产（临产前）的女性。采用原子吸收分光光度法测量产妇和脐带血中锌和铜的含量。两组（每组52对产妇和脐带血样本）的基本特征匹配良好。与剖宫产相比，顺产产妇[87.0（76.1 - 111.4）对76.1（65.2 - 88.3）μg/dL，P = 0.004]和脐带血锌[97.8（87.0 - 114.1）对81.5（65.2 - 110.2）μg/dL，P = 0.034]水平显著更高。虽然产妇铜含量[78.8（48.1 - 106.1）对92.4（51.9 - 114.9）μg/dL，P = 0.759]无显著差异，但顺产时脐带血铜含量[43.5（29.9 - 76.1）对32.2（21.7 - 49.6）μg/dL，P = 0.019]显著更高。锌（产妇和脐带血）与铜之间无显著相关性。虽然脐带血锌与产妇锌显著相关，但产妇和脐带血铜之间无显著相关性。当前研究表明，与剖宫产相比，顺产女性的产妇和脐带血锌以及脐带血铜水平显著更高。
