Racine-Poon A, Dubois J P
Mathematical Applications, CIBA-GEIGY AG, Switzerland.
Stat Med. 1989 Nov;8(11):1327-37. doi: 10.1002/sim.4780081105.
A statistical model is proposed for predicting the range of plasma carbamazepine concentrations after administration of a controlled-release formulation at steady state. The model is based on previous clinical studies in patients with epilepsy. The predicted range may be used to monitor and adjust treatment in a patient.
提出了一种统计模型，用于预测在稳态下给予控释制剂后血浆卡马西平浓度的范围。该模型基于先前对癫痫患者的临床研究。预测范围可用于监测和调整患者的治疗。
