Bühlmann A A
Medizinische Klinik, Universität Zürich.
Schweiz Med Wochenschr. 1989 Nov 18;119(46):1619-23.
The sensation of dyspnea is related to pathologically increased breathing work as a result of hyperventilation and/or increased airway resistance. Low cardiac output resulting in tissue hypoxia provokes hyperventilation. In diffuse interstitial lung diseases, hyperventilation is combined with severely reduced lung compliance. In severe airway obstruction, hypoventilation is the result of excessively enhanced breathing work. Habituation and acute changes of situation have an important bearing on the subjective sensation of dyspnea.
呼吸困难的感觉与因通气过度和/或气道阻力增加导致的病理性呼吸功增加有关。心输出量降低导致组织缺氧会引发通气过度。在弥漫性间质性肺疾病中，通气过度与肺顺应性严重降低同时存在。在严重气道阻塞时，通气不足是呼吸功过度增强的结果。习惯化和情境的急性变化对呼吸困难的主观感觉有重要影响。
