Nowak Zbigniew, Wańkowicz Zofia, Laudanski Krzysztof
Department of Nephrology and Dialysotherapy, Military Institute of Medicine, Warsaw, Poland.
Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, USA.
Med Sci Monit. 2015 Jun 22;21:1798-805. doi: 10.12659/MSM.893331.
It is a struggle to identify the most adaptive coping strategies with disease-mediated stress. Here, we hypothesize that intensity of coping strategies, including denial, in patients with end-stage renal disease (ESRD), varies with type of renal replacement therapy (RRT).
We enrolled 60 in-center hemodialyzed patients (HD) and 55 patients treated with continuous ambulatory peritoneal dialysis (CAPD). We administered the Coping Inventory with Stressful Situation, Profile of Mood States, and Stroop Anxiety Inventory to measure patient coping strategies in the context of their ESRD. Denial defense mechanism was measured via the IBS-R/ED. The Nottingham Health Profile was used to evaluate self-perceived quality of life. Serum potassium, urea, creatinine, phosphorus, calcium, albumin, and hematocrit were utilized as the measurements of adequacy of dialysis.
HD patients had higher self-reported intensity of denial mechanism and avoidance-oriented strategies versus CAPD patients. Because a single strategy is almost never employed, we conducted cluster analysis. We identify 3 patterns of coping strategies using cluster analysis. "Repressors" employed denial and avoidance strategies and were predominant in HD. The second cluster consists of subjects employing predominantly task-oriented strategies with equal distribution among dialyzed patients. The third cluster encompassed a small group of patients who shared higher intensity of both denial and task-oriented strategies. Health-related outcome, anxiety, and mood profile were similar across all patients.
HD patients predominantly used "repressive" strategies. Patients on RRT utilized denial and avoidance-based strategies to achieve satisfactory outcome in terms of perceived quality of life. We conclude that these coping mechanisms that were previously thought to be inferior are beneficial to patient compliance with RRT.
确定应对疾病介导压力的最具适应性的应对策略是一项艰巨的任务。在此,我们假设终末期肾病(ESRD)患者应对策略的强度,包括否认,会因肾脏替代治疗(RRT)的类型而异。
我们招募了60名接受中心血液透析的患者(HD)和55名接受持续性非卧床腹膜透析(CAPD)的患者。我们使用《应激情境应对量表》《情绪状态剖面图》和《斯特鲁普焦虑量表》来测量患者在ESRD背景下的应对策略。通过IBS-R/ED测量否认防御机制。使用《诺丁汉健康量表》评估自我感知的生活质量。血清钾、尿素、肌酐、磷、钙、白蛋白和血细胞比容被用作透析充分性的测量指标。
与CAPD患者相比,HD患者自我报告的否认机制强度和回避导向策略更高。由于几乎从不采用单一策略,我们进行了聚类分析。我们使用聚类分析确定了3种应对策略模式。“压抑者”采用否认和回避策略,在HD患者中占主导地位。第二类由主要采用任务导向策略的受试者组成,在透析患者中分布均匀。第三类包括一小部分同时具有较高否认和任务导向策略强度的患者。所有患者的健康相关结局、焦虑和情绪状况相似。
HD患者主要使用“压抑性”策略。接受RRT的患者利用基于否认和回避的策略,以在自我感知的生活质量方面取得满意的结果。我们得出结论,这些先前被认为较差的应对机制对患者遵守RRT有益。