Zyrianov B N, Musabaeva L I, Lisin V A, Lavrenkov K A, Kitsmaniuk Z D
Vopr Onkol. 1989;35(11):1341-5.
The paper discusses the results of treatment of 128 patients with head and neck cancer in whom fast neutrons (Y-120; approximately 6.2 MeV) were used as a single procedure or in combination with surgery. Tumors of different histomorphologic structure displayed unequal sensitivity to fast neutrons. Mean disease-free survival in patients with complete regression of tumor was 24 months following neutron therapy alone, 18.5 months after combined neutron-photon treatment and 5.5 months only in controls. Relapse rates were 20 and 15% in patients with pre- and postoperative neutron treatment, respectively, as compared to 52% in controls.
本文讨论了128例头颈部癌患者的治疗结果，这些患者接受了快中子（Y - 120；约6.2兆电子伏特）单一治疗或与手术联合治疗。不同组织形态结构的肿瘤对快中子表现出不同的敏感性。肿瘤完全消退的患者，单纯中子治疗后的平均无病生存期为24个月，中子 - 光子联合治疗后为18.5个月，而对照组仅为5.5个月。术前和术后接受中子治疗的患者复发率分别为20%和15%，而对照组为52%。
