痛风结节引发的纤维肉瘤：一例特殊病例报告及文献综述
Fibrosarcoma arising from gouty tophi: report of a unique case and review of literature.
作者信息
Wang Jian-Jun, Wang Hai-Yan, Cheng Kai, Wang Xuan, Yu Bo, Shi Shan-Shan, Zhou Xiao-Jun, Shi Qun-Li
机构信息
Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
出版信息
Int J Clin Exp Pathol. 2015 Apr 1;8(4):4227-32. eCollection 2015.
Fibrosarcoma is a malignant mesenchymal tumor. To the author's best knowledge, no previous case of fibrosarcoma arising from gouty tophi has been reported. Here we reported the first case of fibrosarcoma arising from gouty tophi. A case of 58-year-old man was presented with a mass with ulcer and infection in the second joint of left middle finger for 2 months, with long standing gouty tophi. The tumor was biopsied and the biopsy showed complete excision of the tumor. With the pathological and immunohistochemical features considered, the diagnosis of fibrosarcoma associated with gouty tophi was made. The clinical findings, pathological characteristics and treatment were described.
纤维肉瘤是一种恶性间充质肿瘤。就作者所知，此前尚无痛风石引发纤维肉瘤的病例报道。在此，我们报告首例由痛风石引发的纤维肉瘤病例。一名58岁男性患者，左手中指第二关节处出现伴有溃疡和感染的肿块2个月，有长期痛风石病史。对肿瘤进行活检，活检显示肿瘤已完全切除。综合病理及免疫组化特征，诊断为与痛风石相关的纤维肉瘤。本文描述了其临床症状、病理特征及治疗情况。
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