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[T-激活素治疗复发性丹毒合并湿疹患者]

[T-activin in the treatment of patients with recurrent erysipelas and concomitant eczema].

作者信息

Frolov V M, Peresadin N A, Gaĭdash I S, Baskakov I N, Tishchenko N A

出版信息

Vestn Dermatol Venerol. 1989(9):47-51.

PMID:2609765
Abstract

Increased levels of circulating immune complexes (CIC) have been revealed in 156 patients suffering from erysipelas and chronic eczema, 109 of these with frequent recurrences of erysipelatous inflammation, during all periods of the disease. The maximal rises of CIC levels have been associated with a combination of erysipelas relapse with eczema exacerbation, with the most pathogenic medium- and low-molecular complexes, making up together 80.4 +/- 4% of CICs, predominating in the blood. T-activin therapy results in an essential decrease of CIC level and in 2.5 times reduction of the number of early recurrences of erysipelas.

摘要

在156例患有丹毒和慢性湿疹的患者中,在疾病的各个阶段均发现循环免疫复合物(CIC)水平升高,其中109例丹毒样炎症频繁复发。CIC水平的最大升高与丹毒复发和湿疹加重相关,血液中致病性最强的中低分子复合物占CIC的80.4±4%。T-激活素治疗可使CIC水平显著降低,并使丹毒早期复发次数减少2.5倍。

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