Estrogen and Cardiovascular Disease: Is Timing Everything?
作者信息
Giordano Samantha, Hage Fadi G, Xing Dongqi, Chen Yiu-Fai, Allon Steven, Chen Chongjia, Oparil Suzanne
机构信息
Vascular Biology and Hypertension Program, Division of Cardiovascular Disease (SG, FGH, DX, Y-FC, SA, C-JC, SO), Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama; and Division of Cardiology (FGH), Birmingham Veterans Affairs Medical Center, Birmingham, Alabama.
出版信息
Am J Med Sci. 2015 Jul;350(1):27-35. doi: 10.1097/MAJ.0000000000000512.
Abstract
摘要
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G protein-coupled estrogen receptor protects from atherosclerosis.G蛋白偶联雌激素受体可预防动脉粥样硬化。
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Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis.来自雌二醇早期与晚期干预试验的方法和基线心血管数据，该试验检验绝经激素时机假说。
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Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial.近期绝经女性的动脉成像结果和心血管危险因素：一项随机试验。
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Estrogen effects on vascular inflammation are age dependent: role of estrogen receptors.雌激素对血管炎症的影响具有年龄依赖性：雌激素受体的作用。
Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1477-1485. doi: 10.1161/ATVBAHA.114.303629. Epub 2014 May 29.
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Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials.绝经激素治疗与妇女健康倡议随机试验干预和停药后扩展阶段的健康结局。
JAMA. 2013 Oct 2;310(13):1353-68. doi: 10.1001/jama.2013.278040.
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