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使用空气和氮氧混合气进行饱和度减压编程的扩展氧窗概念

The Extended Oxygen Window Concept for Programming Saturation Decompressions Using Air and Nitrox.

作者信息

Kot Jacek, Sicko Zdzislaw, Doboszynski Tadeusz

机构信息

National Centre for Hyperbaric Medicine, Institute of Maritime and Tropical Medicine, Medical University of Gdansk, Powstania Styczniowego, Gdynia, Poland.

出版信息

PLoS One. 2015 Jun 25;10(6):e0130835. doi: 10.1371/journal.pone.0130835. eCollection 2015.

Abstract

Saturation decompression is a physiological process of transition from one steady state, full saturation with inert gas at pressure, to another one: standard conditions at surface. It is defined by the borderline condition for time spent at a particular depth (pressure) and inert gas in the breathing mixture (nitrogen, helium). It is a delicate and long lasting process during which single milliliters of inert gas are eliminated every minute, and any disturbance can lead to the creation of gas bubbles leading to decompression sickness (DCS). Most operational procedures rely on experimentally found parameters describing a continuous slow decompression rate. In Poland, the system for programming of continuous decompression after saturation with compressed air and nitrox has been developed as based on the concept of the Extended Oxygen Window (EOW). EOW mainly depends on the physiology of the metabolic oxygen window--also called inherent unsaturation or partial pressure vacancy--but also on metabolism of carbon dioxide, the existence of water vapor, as well as tissue tension. Initially, ambient pressure can be reduced at a higher rate allowing the elimination of inert gas from faster compartments using the EOW concept, and maximum outflow of nitrogen. Then, keeping a driving force for long decompression not exceeding the EOW allows optimal elimination of nitrogen from the limiting compartment with half-time of 360 min. The model has been theoretically verified through its application for estimation of risk of decompression sickness in published systems of air and nitrox saturation decompressions, where DCS cases were observed. Clear dose-reaction relation exists, and this confirms that any supersaturation over the EOW creates a risk for DCS. Using the concept of the EOW, 76 man-decompressions were conducted after air and nitrox saturations in depth range between 18 and 45 meters with no single case of DCS. In summary, the EOW concept describes physiology of decompression after saturation with nitrogen-based breathing mixtures.

摘要

饱和减压是一个生理过程,即从一种稳定状态(在压力下完全被惰性气体饱和)转变为另一种状态:海平面的标准条件。它由在特定深度(压力)停留的时间以及呼吸混合气中的惰性气体(氮气、氦气)的临界条件所定义。这是一个微妙且持久的过程,在此过程中每分钟都会有单毫升的惰性气体被排出,任何干扰都可能导致气泡形成,进而引发减压病(DCS)。大多数操作程序依赖于通过实验得出的参数,这些参数描述了持续缓慢的减压速率。在波兰,基于扩展氧窗(EOW)的概念,开发了用于压缩空气和氮氧混合气饱和后连续减压编程的系统。EOW主要取决于代谢氧窗的生理学——也称为固有不饱和或分压空位——但也取决于二氧化碳的代谢、水蒸气的存在以及组织张力。最初,可以以较高的速率降低环境压力,利用EOW概念从较快的隔室中排出惰性气体,并实现氮气的最大流出量。然后,在不超过EOW的情况下保持长时间减压的驱动力,可使半衰期为360分钟的极限隔室中的氮气得到最佳排出。该模型已通过应用于已发表的空气和氮氧混合气饱和减压系统中减压病风险的估计进行了理论验证,在这些系统中观察到了DCS病例。存在明确的剂量反应关系,这证实了超过EOW的任何过饱和都会产生DCS风险。利用EOW概念,在18至45米深度范围内进行了76次空气和氮氧混合气饱和后的人体减压,未出现一例DCS。总之,EOW概念描述了基于氮气的呼吸混合气饱和后减压的生理学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f072/4482426/60b148dbe689/pone.0130835.g001.jpg

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