聚合酶链反应（PCR）检测对澳大利亚流感和百日咳通报的贡献。

The contribution of PCR testing to influenza and pertussis notifications in Australia.

作者信息

Kaczmarek M C, Ware R S, Lambert S B

机构信息

Queensland Children's Medical Research Institute,Brisbane,QLD,Australia.

School of Public Health,The University of Queensland,Herston,QLD,Australia.

出版信息

Epidemiol Infect. 2016 Jan;144(2):306-14. doi: 10.1017/S0950268815001004. Epub 2015 Jun 26.

DOI:10.1017/S0950268815001004

PMID:26112983

Abstract

Influenza and pertussis are the two most common vaccine-preventable infections notified in Australia. We assessed the role of polymerase chain reaction (PCR) diagnosis in influenza and pertussis cases notified to the Australian National Notifiable Diseases Surveillance System (NNDSS). There were a total of 2 10 786 notified influenza cases (2001-2013) and 2 55 866 notified pertussis cases (1991-2013). After 1 January 2007, the majority of influenza and pertussis notifications were PCR-based (80·5% and 59·6%, respectively). Before 31 December 2006, PCR-based notifications were limited (29·1% and 11·7%, respectively). By 2013, PCR-based notifications had largely replaced all other diagnostic methods, with the exception of serology-based notifications in pertussis cases in adults aged ⩾ 25 years.

摘要

流感和百日咳是澳大利亚通报的两种最常见的可通过疫苗预防的感染性疾病。我们评估了聚合酶链反应（PCR）诊断在通报给澳大利亚国家法定传染病监测系统（NNDSS）的流感和百日咳病例中的作用。2001年至2013年期间共通报了210786例流感病例，1991年至2013年期间共通报了255866例百日咳病例。2007年1月1日之后，大多数流感和百日咳通报是基于PCR的（分别为80.5%和59.6%）。2006年12月31日之前，基于PCR的通报较少（分别为29.1%和11.7%）。到2013年，基于PCR的通报已基本取代了所有其他诊断方法，但25岁及以上成年人百日咳病例中基于血清学的通报除外。