Centre for Musculoskeletal Research, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester,
Centre for Rheumatology, Royal Free Hospital, London.
Rheumatology (Oxford). 2015 Nov;54(11):2015-24. doi: 10.1093/rheumatology/kev201. Epub 2015 Jun 26.
Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by patients with SSc. However, there is a limited evidence base to guide clinicians in the management of SSc-related digital vasculopathy. Our aim was to produce recommendations that would be helpful for clinicians, especially for those managing patients outside specialist centres.
The UK Scleroderma Study Group set up several working groups to develop a number of consensus best practice pathways for the management of SSc-specific complications, including digital vasculopathy.
This overview presents the background and best practice consensus pathways for SSc-related RP, digital ulceration and critical ischaemia. Examples of drug therapies, including doses, are suggested in order to inform prescribing practice.
A number of treatment algorithms are provided that are intended to provide the clinician with accessible reference tools for use in daily management.
数字血管病（包括 RP、指溃疡和临界性缺血）是引起 SSc 患者疼痛和残疾的主要原因。然而，目前指导临床医生治疗 SSc 相关数字血管病的证据有限。我们的目的是提出有助于临床医生的建议，特别是对那些在专科中心之外管理患者的医生。
英国硬皮病研究组成立了多个工作组，制定了一些共识最佳实践途径，以管理 SSc 特定的并发症，包括数字血管病。
本综述介绍了 SSc 相关 RP、指溃疡和临界性缺血的背景和最佳实践共识途径。为了告知处方实践，建议了药物治疗的例子，包括剂量。
提供了一些治疗算法，旨在为临床医生提供日常管理中使用的易于访问的参考工具。
