Denton Christopher P, De Lorenzis Enrico, Roblin Elen, Goldman Nina, Alcacer-Pitarch Begonya, Blamont Emma, Buch Maya, Carulli Maresa, Cotton Caroline, Del Galdo Francesco, Derrett-Smith Emma, Douglas Karen, Farrington Sue, Fligelstone Kim, Gompels Luke, Griffiths Bridget, Herrick Ariane, Hughes Michael, Pain Clare, Pantano Georgina, Pauling John, Prabu Athiveeraramapandian, O'Donoghue Nuala, Renzoni Elisabetta, Royle Jeremy, Samaranayaka Muditha, Spierings Julia, Tynan Aoife, Warburton Louise, Ong Voon
Centre for Rheumatology, Division of Medicine, University College London, London, UK.
Department of Rheumatology, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
Rheumatol Adv Pract. 2023 Mar 14;7(1):rkad022. doi: 10.1093/rap/rkad022. eCollection 2023.
This guideline will provide a practical roadmap for management of SSc that builds upon the previous treatment guideline to incorporate advances in evidence-based treatment and increased knowledge about assessment, classification and management. General approaches to management as well as treatment of specific complications will be covered, including lung, cardiac, renal and gastrointestinal tract disease, as well as RP, digital vasculopathy, skin manifestations, calcinosis and impact on quality of life. It will include guidance related to emerging approved therapies for interstitial lung disease and account for National Health Service England prescribing policies and national guidance relevant to SSc. The guideline will be developed using the methods and processes outlined in Creating Clinical Guidelines: Our Protocol. This development process to produce guidance, advice and recommendations for practice has National Institute for Health and Care Excellence accreditation.
本指南将提供一份系统性硬化症管理的实用路线图，它以先前的治疗指南为基础，纳入循证治疗的进展以及对评估、分类和管理的更多认识。将涵盖一般管理方法以及特定并发症的治疗，包括肺部、心脏、肾脏和胃肠道疾病，以及雷诺现象、指端血管病变、皮肤表现、钙质沉着症和对生活质量的影响。它将包括与间质性肺病新获批疗法相关的指导，并考虑英格兰国民医疗服务体系的处方政策以及与系统性硬化症相关的国家指南。本指南将采用《制定临床指南：我们的方案》中概述的方法和流程来制定。这一为实践提供指导、建议和推荐的制定过程已获得英国国家卫生与临床优化研究所的认可。
