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营养性维生素A缺乏继发颅骨骨质增生所致的单侧压迫性视神经病变。

Unilateral compressive optic neuropathy due to skull hyperostosis secondary to nutritional vitamin A deficiency.

作者信息

Zayed Mohammed G, Hickman Simon J, Batty Ruth, McCloskey Eugene V, Pepper Irene M

机构信息

Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.

Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK.

出版信息

Clin Cases Miner Bone Metab. 2015 Jan-Apr;12(1):75-7. doi: 10.11138/ccmbm/2015.12.1.075.

DOI:10.11138/ccmbm/2015.12.1.075
PMID:26136803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4469234/
Abstract

We report a 17-year-old boy who presented with a chronic left unilateral optic neuropathy. Computerized tomography and magnetic resonance imaging demonstrated compression of the left optic nerve due to skull hyperostosis. He was found to be profoundly vitamin A deficient secondary to an unusual diet consisting predominantly of potato chips and crisps. Skull hyperostosis with cranial neuropathies and other neurological abnormalities has been described in growing animals fed vitamin A deficient diets but has not been previously reported in humans.

摘要

我们报告了一名17岁男孩,他患有慢性左侧单侧视神经病变。计算机断层扫描和磁共振成像显示由于颅骨骨质增生导致左侧视神经受压。发现他因主要由薯片组成的特殊饮食而严重缺乏维生素A。在喂食维生素A缺乏饮食的生长动物中已描述了伴有颅神经病变和其他神经异常的颅骨骨质增生,但此前尚未在人类中报道过。

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