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网膜移植改善大鳞状细胞癌手术效果:一例报告

Omental transplantation improves surgical outcome of large squamous cell carcinoma: A case report.

作者信息

Li Xianan, Ouyang Zhengxiao, Yang Shuo, Zhai Zanjing, Li Haowei, Kang Zhong-Cheng, Li Zan

机构信息

Department of Orthopedics, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410012, P.R. China.

Department of Orthopedics, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410012, P.R. China ; Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, P.R. China.

出版信息

Oncol Lett. 2015 Jun;9(6):2805-2808. doi: 10.3892/ol.2015.3089. Epub 2015 Mar 31.

DOI:10.3892/ol.2015.3089
PMID:26137151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4473671/
Abstract

Cutaneous squamous cell carcinoma (SCC) is an major health issue due to the significant health costs and marked disfigurement following surgical excision. The conventional reconstructive options may not be suitable for patients with large SCCs of the lower part of the leg, due to the regional tissue damage and ischemic environment. The omental transposition flap is a highly vascularized tissue that is resistant to infection and provides a recipient bed for skin grafts. This is the case report of a male patient with a large SCC in the lower part of his right leg, which was treated with extensive resection. The patient subsequently underwent reconstruction using a free omental flap, followed by transplantation of a secondary skin graft. The patient did not experience recurrence or metastasis during the 2 years of follow-up, indicating that, when dealing with postoperative skin cancer defects in an ischemic environment, omental transplantation may be a viable treatment option.

摘要

皮肤鳞状细胞癌(SCC)是一个重大的健康问题,因为手术切除后会产生高昂的医疗费用并导致明显的毁容。由于局部组织损伤和缺血环境,传统的重建方法可能不适用于小腿下部患有大面积SCC的患者。网膜转位皮瓣是一种血管丰富的组织,具有抗感染能力,并为皮肤移植提供受区床。本文报告了一名男性患者,其右小腿下部患有大面积SCC,接受了广泛切除治疗。该患者随后使用游离网膜皮瓣进行重建,随后进行了二期皮肤移植。在2年的随访中,患者未出现复发或转移,这表明在处理缺血环境中的术后皮肤癌缺损时,网膜移植可能是一种可行的治疗选择。

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本文引用的文献

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