Goldman G D
University of Vermont College of Medicine, Fletcher-Allen Health Care, Burlington 05401, USA.
Semin Cutan Med Surg. 1998 Jun;17(2):80-95. doi: 10.1016/s1085-5629(98)80002-3.
Cutaneous squamous cell carcinoma (SCC) is the second most common form of skin cancer and is treated frequently by dermatologists. For many years, the level of knowledge regarding treatment of SCC has taken a backseat to the treatment of basal cell carcinoma and malignant melanoma. As dermatologists become more surgically proficient and assume a leading role in the surgical care for cutaneous carcinoma, a thorough knowledge of the appropriate management of SCC is of paramount importance. In particular, it is essential to recognize that, unlike basal cell carcinoma, certain SCC have a significant metastatic potential and require more comprehensive care. This review targets the etiology, pathogenesis, clinical presentation, histopathology, and treatment of SCC. Particular attention is focused on providing appropriate care for SCC and recognizing and arranging appropriate management for high risk SCC.
皮肤鳞状细胞癌（SCC）是第二常见的皮肤癌形式，皮肤科医生经常对其进行治疗。多年来，关于SCC治疗的知识水平一直落后于基底细胞癌和恶性黑色素瘤的治疗。随着皮肤科医生手术技能的提高并在皮肤癌的手术治疗中发挥主导作用，全面了解SCC的适当管理至关重要。特别是，必须认识到，与基底细胞癌不同，某些SCC具有显著的转移潜能，需要更全面的治疗。本综述针对SCC的病因、发病机制、临床表现、组织病理学和治疗。特别关注为SCC提供适当的治疗，以及识别和安排对高危SCC的适当管理。
