Zhong Tuhua, Oporto Gloria S, Jaczynski Jacek, Jiang Changle
Division of Forestry and Natural Resources, West Virginia University, Morgantown, WV 26506, USA.
Division of Animal and Nutritional Sciences, West Virginia University, Morgantown, WV 26506, USA.
Biomed Res Int. 2015;2015:456834. doi: 10.1155/2015/456834. Epub 2015 Jun 2.
Our long-term goal is to develop a hybrid cellulose-copper nanoparticle material as a functional nanofiller to be incorporated in thermoplastic resins for efficiently improving their antimicrobial properties. In this study, copper nanoparticles were first synthesized through chemical reduction of cupric ions on TEMPO nanofibrillated cellulose (TNFC) template using borohydride as a copper reducing agent. The resulting hybrid material was embedded into a polyvinyl alcohol (PVA) matrix using a solvent casting method. The morphology of TNFC-copper nanoparticles was analyzed by transmission electron microscopy (TEM); spherical copper nanoparticles with average size of 9.2 ± 2.0 nm were determined. Thermogravimetric analysis and antimicrobial performance of the films were evaluated. Slight variations in thermal properties between the nanocomposite films and PVA resin were observed. Antimicrobial analysis demonstrated that one-week exposure of nonpathogenic Escherichia coli DH5α to the nanocomposite films results in up to 5-log microbial reduction.
我们的长期目标是开发一种纤维素-铜纳米颗粒混合材料，作为一种功能性纳米填料，用于掺入热塑性树脂中，以有效提高其抗菌性能。在本研究中，首先通过使用硼氢化钠作为铜还原剂，在TEMPO纳米纤化纤维素（TNFC）模板上化学还原铜离子来合成铜纳米颗粒。使用溶液浇铸法将所得的混合材料嵌入聚乙烯醇（PVA）基质中。通过透射电子显微镜（TEM）分析TNFC-铜纳米颗粒的形态；确定了平均尺寸为9.2±2.0nm的球形铜纳米颗粒。评估了薄膜的热重分析和抗菌性能。观察到纳米复合薄膜和PVA树脂之间的热性能略有差异。抗菌分析表明，非致病性大肠杆菌DH5α在纳米复合薄膜上暴露一周导致微生物减少高达5个对数。
