Rosenström Tom, Elovainio Marko, Jokela Markus, Pirkola Sami, Koskinen Seppo, Lindfors Olavi, Keltikangas-Järvinen Liisa
Institute of Behavioural Sciences, University of Helsinki, Finland.
National Institute for Health and Welfare, Helsinki, Finland.
Int J Methods Psychiatr Res. 2015 Sep;24(3):213-25. doi: 10.1002/mpr.1478. Epub 2015 Jul 3.
Concordance between sum scores of self-reported depressive symptoms and structured interview diagnoses has been studied extensively, but are these the best attainable self-report-based predictions for interview diagnoses? We maximized the cross-validated concordance between World Health Organization's Composite International Diagnostic Interview (CIDI) diagnosis and Beck's Depression Inventory (BDI), and General Health Questionnaire (GHQ), from the viewpoint of exploratory statistics, re-analysing Health 2000 general-population sample of adults over 30 years in mainland Finland (N = 5200-5435). BDI sum-score prediction of CIDI diagnosis could be superseded by using (1) weighted sums of items, (2) classification trees constructed from items, or (3) a single item. Best solution (2) yielded cross-validated Youden's Index 0.757 [standard error (SE) = 0.001, sensitivity = 0.907, specificity = 0.851], improving the concordance to 1.07-fold (1.18-fold for 12-month diagnosis). A single-item solution was best for the GHQ. All positive predictive values remained low (0.09-0.31). Thus, CIDI-to-questionnaire concordance can be improved by using all information in the questionnaires instead of just sum scores, but latent-trait theory for questionnaires is incompatible with interview diagnoses (single item achieved better concordance than summing all). Self-reports have low predictive value for CIDI diagnoses in the general population, but better in settings with higher major depressive disorder (MDD) base rates. Copyright © 2015 John Wiley & Sons, Ltd.
自我报告的抑郁症状总分与结构化访谈诊断之间的一致性已经得到了广泛研究,但这些是基于自我报告对访谈诊断所能获得的最佳预测吗?我们从探索性统计的角度,最大化了世界卫生组织综合国际诊断访谈(CIDI)诊断与贝克抑郁量表(BDI)以及一般健康问卷(GHQ)之间的交叉验证一致性,重新分析了芬兰大陆30岁以上成年人的2000年健康普查样本(N = 5200 - 5435)。使用(1)项目加权总和、(2)由项目构建的分类树或(3)单个项目,可以取代BDI总分对CIDI诊断的预测。最佳解决方案(2)产生的交叉验证约登指数为0.757[标准误差(SE)= 0.001,灵敏度 = 0.907,特异度 = 0.851],将一致性提高到1.07倍(12个月诊断为1.18倍)。单个项目的解决方案对GHQ是最佳的。所有阳性预测值仍然很低(0.09 - 0.31)。因此,通过使用问卷中的所有信息而不仅仅是总分,可以提高CIDI与问卷之间的一致性,但问卷的潜在特质理论与访谈诊断不兼容(单个项目比汇总所有项目具有更好的一致性)。自我报告在一般人群中对CIDI诊断的预测价值较低,但在重度抑郁症(MDD)患病率较高的环境中预测价值更好。版权所有© 2015约翰威立父子有限公司。