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输尿管肾盂连接部梗阻患儿肾盂成形术年龄相关因素。

Factors associated with age at pyeloplasty in children with ureteropelvic junction obstruction.

作者信息

Vemulakonda Vijaya M, Wilcox Duncan T, Crombleholme Timothy M, Bronsert Michael, Kempe Allison

机构信息

Department of Pediatric Urology, Children's Hospital Colorado, 13123 E. 16th Ave, Campus Box B-463, Aurora, CO, USA,

出版信息

Pediatr Surg Int. 2015 Sep;31(9):871-7. doi: 10.1007/s00383-015-3748-2. Epub 2015 Jul 5.

Abstract

OBJECTIVES

Our objectives were to: (1) delineate factors associated with surgery at <1 year and (2) determine if early intervention was associated with increased risk of readmission.

METHODS

We conducted a retrospective review of children age 0-18 years with a diagnosis of UPJ obstruction who underwent pyeloplasty from 1/1/1999 to 9/1/2009 using the PHIS database. Data collected included patient factors (race, gender, insurance type, APR-DRG severity of illness) and hospital factors (annual case volume, census region, academic status). Outcomes assessed were: age at surgery and hospital readmission within 1 year of surgery. Data were analyzed using logistic regression and Cox PH for multivariate analyses.

RESULTS

4499 children met study criteria. Minority race (OR 1.55), male gender (OR 1.49), public insurance (OR 1.37), high severity of illness (OR 3.60), Southern region (OR 1.44), and low hospital volume (OR 1.37) were significant predictors of early surgery (p < 0.05). Only early surgery (HR 2.42; 95% CI 1.67-3.49 2.42) was associated with increased risk of readmission.

CONCLUSIONS

In children with UPJ obstruction, age at surgery is associated with patient demographic and hospital factors. Early surgery is associated with higher rates of readmission, suggesting that variations in age at surgery may be associated with significant differences in outcomes.

摘要

目的

我们的目的是:(1)确定与1岁前手术相关的因素,以及(2)确定早期干预是否与再入院风险增加相关。

方法

我们使用PHIS数据库对1999年1月1日至2009年9月1日期间诊断为肾盂输尿管连接部梗阻并接受肾盂成形术的0至18岁儿童进行了回顾性研究。收集的数据包括患者因素(种族、性别、保险类型、APR-DRG疾病严重程度)和医院因素(年度病例数量、普查区域、学术地位)。评估的结果为:手术年龄和术后1年内的医院再入院情况。使用逻辑回归和Cox PH进行多变量分析。

结果

4499名儿童符合研究标准。少数族裔(比值比1.55)、男性(比值比1.49)、公共保险(比值比1.37)、疾病严重程度高(比值比3.60)、南部地区(比值比1.44)和医院病例数量少(比值比1.37)是早期手术的显著预测因素(p<0.05)。只有早期手术(风险比2.42;95%置信区间1.67 - 3.49)与再入院风险增加相关。

结论

在肾盂输尿管连接部梗阻的儿童中,手术年龄与患者人口统计学和医院因素相关。早期手术与更高的再入院率相关,这表明手术年龄的差异可能与结局的显著差异相关。

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