Boucher Jean, Lucca Joan, Hooper Catherine, Pedulla Lillian, Berry Donna L
Phyllis F. Cantor Center at Dana-Farber Cancer Institute in Boston, MA, and the University of Massachusetts Worcester Graduate School of Nursing.
Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute.
Oncol Nurs Forum. 2015 Jul;42(4):383-9. doi: 10.1188/15.ONF.383-389.
PURPOSE/OBJECTIVES: To evaluate a nurse-led intervention to enhance medication knowledge and adherence using the Multinational Association for Supportive Care in Cancer Oral Agent Teaching Tool (MOATT).
Longitudinal, descriptive feasibility study.
An ambulatory thoracic oncology disease center located at the Dana-Farber Cancer Institute in Boston, MA.
30 adult patients with lung cancer who received the oral agent erlotinib.
Structured, nurse-led education sessions using the MOATT were provided, with a 72-hour follow-up telephone contact. Participants completed a Knowledge Rating Scale (KRS) and adapted Morisky Medication Adherence Scale-8 (MMAS-8) at the end of the first cycle of oral chemotherapy.
Knowledge and adherence; feasibility.
Twenty-seven participants completed the study outcome measures reporting high knowledge levels and MMAS-8 scores. Structured, nurse-led education and follow-up monitoring sessions ranged from 14-30 minutes. Several participants also initiated contact for assistance with prescription procurement and symptom management. Participants reported a median of two side effects.
The structured, nurse-led teaching, using the MOATT tool, and follow-up nurse contacts were feasible as integrated into the thoracic oncology setting. Adherence and knowledge outcomes were encouraging. Additional studies should include objective adherence measures and strategies for delivering supportive care to patients at home.
Structured teaching with patients is important to enhance proper oral anticancer medication knowledge and adherence, including follow-up monitoring of administration and side effects at 72 hours.
目的/目标：使用癌症口服药物教学工具多国支持性护理协会（MOATT）评估由护士主导的干预措施，以提高用药知识和依从性。
纵向描述性可行性研究。
位于马萨诸塞州波士顿市达纳-法伯癌症研究所的门诊胸科肿瘤疾病中心。
30名接受口服药物厄洛替尼治疗的成年肺癌患者。
使用MOATT提供由护士主导的结构化教育课程，并进行72小时的随访电话联系。参与者在口服化疗的第一个周期结束时完成知识评分量表（KRS）和改编后的莫利斯基药物依从性量表-8（MMAS-8）。
知识和依从性；可行性。
27名参与者完成了研究结果测量，报告了较高的知识水平和MMAS-8评分。由护士主导的结构化教育和随访监测课程时长为14 - 30分钟。几名参与者还主动联系寻求处方获取和症状管理方面的帮助。参与者报告的副作用中位数为两种。
使用MOATT工具由护士主导的结构化教学以及护士随访在胸科肿瘤环境中是可行的。依从性和知识结果令人鼓舞。进一步的研究应包括客观的依从性测量以及为居家患者提供支持性护理的策略。
对患者进行结构化教学对于提高正确的口服抗癌药物知识和依从性很重要，包括在72小时时对用药和副作用进行随访监测。
