Spoelstra Sandra L, Sikorskii Alla, Majumder Atreyee, Burhenn Peggy S, Schueller Monica, Given Barbara
Michigan State University in East Lansing.
University of Arizona.
Clin J Oncol Nurs. 2017 Apr 1;21(2):157-160. doi: 10.1188/17.CJON.157-160.
Symptom burden and poor adherence to oral anticancer agents remain significant clinical problems. This study examined feasibility, preliminary efficacy, and satisfaction with ADHERE, a nurse practitioner intervention that promotes symptom management and adherence among patients prescribed oral agents. The intervention group (which received one semistructured, face-to-face session followed by three weekly telephone sessions using motivational interviewing, brief cognitive-behavioral therapy, and a toolkit to promote self-management) had significantly lower symptom severity postintervention. Self-reported adherence was high and did not differ by group. Patients reported being highly satisfied with the ADHERE intervention. .
症状负担以及口服抗癌药物依从性差仍然是严重的临床问题。本研究考察了ADHERE的可行性、初步疗效及满意度，ADHERE是一种由执业护士实施的干预措施，旨在促进口服药物治疗患者的症状管理及依从性。干预组（接受一次半结构化面对面访谈，随后通过动机性访谈、简短认知行为疗法及促进自我管理的工具包进行三次每周一次的电话访谈）干预后症状严重程度显著降低。自我报告的依从性较高，且两组间无差异。患者报告对ADHERE干预高度满意。
