Pazienza Valerio, Panebianco Concetta, Andriulli Angelo
Gastroenterology Unit, Fondazione "Casa Sollievo della Sofferenza" IRCCS Hospital, San Giovanni Rotondo, FG, Italy.
Clin Exp Med. 2016 Aug;16(3):265-72. doi: 10.1007/s10238-015-0372-3. Epub 2015 Jul 7.
Hepatitis B virus (HBV), hepatitis C virus (HCV) and Delta (HDV) infections are a global health burden. With different routes of infection and biology, HBV, HCV and HDV are capable to induce liver cirrhosis and cancer by impinging on epigenetic mechanisms altering host cell's pathways. In the present manuscript, we reviewed the published studies taking into account the relationship between the hepatitis viruses and the DNA methyltransferases proteins.
乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）和丁型肝炎病毒（HDV）感染是一项全球卫生负担。HBV、HCV和HDV具有不同的感染途径和生物学特性，能够通过影响表观遗传机制改变宿主细胞通路，进而诱发肝硬化和癌症。在本论文中，我们回顾了已发表的研究，考量了肝炎病毒与DNA甲基转移酶蛋白之间的关系。
