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雌二醇对大鼠阴道上皮细胞膜流动性的影响。

Effect of estradiol on the membrane fluidity of the rat vaginal epithelial cells.

作者信息

Reddy A G, Shivaji S, Gupta P D

机构信息

Centre for Cellular & Molecular Biology, Hyderabad, India.

出版信息

J Steroid Biochem. 1989 Dec;33(6):1229-33. doi: 10.1016/0022-4731(89)90434-2.

DOI:10.1016/0022-4731(89)90434-2
PMID:2615367
Abstract

Changes in the cell surface of vaginal epithelial cells were studied by scanning microscopy and fluorescence spectroscopy. Microvilli which are prominent features of the vaginal epithelial cells in proestrus and diestrus are replaced by sheet-like structures in the estrus phase. Surface morphology of vaginal epithelial cells of estradiol primed rat resembles the vaginal cells from estrus phase rats whereas vaginal cells from control rats resembles the diestrus phase. Measurement of the fluidity of the membranes indicated that the vaginal epithelial cell membrane of estrus rats is more fluid compared to proestrus and diestrus. Similarly, estradiol primed immature rat vaginal epithelial cell membrane was observed to be more fluid than the corresponding control.

摘要

通过扫描显微镜和荧光光谱法研究了阴道上皮细胞表面的变化。在动情前期和动情后期,微绒毛是阴道上皮细胞的显著特征,而在发情期则被片状结构所取代。用雌二醇预处理的大鼠阴道上皮细胞的表面形态类似于发情期大鼠的阴道细胞,而对照大鼠的阴道细胞则类似于动情后期。膜流动性的测量表明,与动情前期和动情后期相比,发情期大鼠的阴道上皮细胞膜流动性更强。同样,观察到用雌二醇预处理的未成熟大鼠阴道上皮细胞膜比相应的对照更具流动性。

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