呼吸严重程度评分可区分上呼吸道感染和下呼吸道感染，并预测疾病严重程度指标。
Respiratory Severity Score Separates Upper Versus Lower Respiratory Tract Infections and Predicts Measures of Disease Severity.
作者信息
Feldman Amy S, Hartert Tina V, Gebretsadik Tebeb, Carroll Kecia N, Minton Patricia A, Woodward Kimberly B, Larkin Emma K, Miller Eva Kathryn, Valet Robert S
机构信息
Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, and Center for Asthma and Environmental Sciences Research, Vanderbilt University School of Medicine , Nashville, Tennessee.
Department of Biostatistics, Vanderbilt University School of Medicine , Nashville, Tennessee.
出版信息
Pediatr Allergy Immunol Pulmonol. 2015 Jun 1;28(2):117-120. doi: 10.1089/ped.2014.0463.
Abstract
A respiratory severity score (RSS) describing acute respiratory illness (ARI) severity would be useful for research and clinical purposes. A total of 630 term infants presenting with ARI had their RSS measured. RSS was higher in those with lower respiratory tract infection (LRTI) compared with those with upper respiratory infection (URI; LRTI 6.5 [4-8.5]; URI 1 [0-2], <0.001) and in hospitalized infants compared with outpatients (hospitalized 6.5 [4-9]; outpatient 1 [0-3], <0.001). RSS is higher in LRTI compared with URI and in hospitalized compared with nonhospitalized infants.
摘要
一种描述急性呼吸道疾病（ARI）严重程度的呼吸严重程度评分（RSS）对于研究和临床目的将是有用的。共有630名患有ARI的足月儿接受了RSS测量。与上呼吸道感染（URI）患儿相比，下呼吸道感染（LRTI）患儿的RSS更高（LRTI为6.5[4 - 8.5]；URI为1[0 - 2]，P<0.001）；与门诊患儿相比，住院患儿的RSS更高（住院患儿为6.5[4 - 9]；门诊患儿为1[0 - 3]，P<0.001）。与URI患儿相比，LRTI患儿的RSS更高；与非住院患儿相比，住院患儿的RSS更高。
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本文引用的文献
1
Severity scoring systems: are they internally valid, reliable and predictive of oxygen use in children with acute bronchiolitis?
Pediatr Pulmonol. 2013 Aug;48(8):797-803. doi: 10.1002/ppul.22627. Epub 2012 Sep 4.
2
Human rhinovirus species and season of infection determine illness severity.
Am J Respir Crit Care Med. 2012 Nov 1;186(9):886-91. doi: 10.1164/rccm.201202-0330OC. Epub 2012 Aug 23.
3
Evidence for a causal relationship between allergic sensitization and rhinovirus wheezing in early life.
Am J Respir Crit Care Med. 2012 Feb 1;185(3):281-5. doi: 10.1164/rccm.201104-0660OC. Epub 2011 Sep 29.
4
The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases.
Respirology. 2010 May;15(4):691-9. doi: 10.1111/j.1440-1843.2010.01743.x. Epub 2010 Mar 29.
5
The severity-dependent relationship of infant bronchiolitis on the risk and morbidity of early childhood asthma.
J Allergy Clin Immunol. 2009 May;123(5):1055-61, 1061.e1. doi: 10.1016/j.jaci.2009.02.021. Epub 2009 Apr 10.
6
Infectious disease hospitalizations among infants in the United States.
Pediatrics. 2008 Feb;121(2):244-52. doi: 10.1542/peds.2007-1392.
7
Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma.
J Allergy Clin Immunol. 2007 May;119(5):1105-10. doi: 10.1016/j.jaci.2006.12.669. Epub 2007 Mar 13.
8
Rhinovirus illnesses during infancy predict subsequent childhood wheezing.
J Allergy Clin Immunol. 2005 Sep;116(3):571-7. doi: 10.1016/j.jaci.2005.06.024.
9
Rhinovirus-induced wheezing in infancy--the first sign of childhood asthma?
J Allergy Clin Immunol. 2003 Jan;111(1):66-71. doi: 10.1067/mai.2003.33.
10
Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7.
Am J Respir Crit Care Med. 2000 May;161(5):1501-7. doi: 10.1164/ajrccm.161.5.9906076.
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