Tabaraud F, Hugon J, Salle J Y, Boulesteix J M, Rigaud M, Vallat J M, Dumas M
Department of Neurology, University Hospital, Limoges, France.
Neurophysiol Clin. 1989 Dec;19(6):433-41. doi: 10.1016/s0987-7053(89)80001-2.
Central motor conduction was investigated by way of magneto-electric cortico-spinal stimulation in 6 patients with sporadic olivo-ponto-cerebellar atrophy. Two patients were found to have reduced leucocyte GDH activity. Only the 3 patients with corticospinal deficits displayed increased central conduction rates, which were predominant in the lower limbs. The duration of the disease is statistically longer in patients with corticospinal deficit compared to patients with no corticospinal deficit. In OPCA, evoked motor potentials are useful in assessing the corticospinal deficit which does not appear to be linked to reduced leucocyte GDH activity.
通过磁电皮质脊髓刺激对6例散发性橄榄体脑桥小脑萎缩患者的中枢运动传导进行了研究。发现2例患者白细胞谷氨酸脱氢酶（GDH）活性降低。只有3例存在皮质脊髓功能缺损的患者显示中枢传导速度加快，且以下肢为主。与无皮质脊髓功能缺损的患者相比，存在皮质脊髓功能缺损的患者病程在统计学上更长。在橄榄体脑桥小脑萎缩（OPCA）中，诱发电位有助于评估皮质脊髓功能缺损，而这似乎与白细胞GDH活性降低无关。
