Abasov I T, Iof I M
Acta Hepatogastroenterol (Stuttg). 1978 Apr;25(2):144-9.
The changes in gastric secretion following administration of different preparations have been studied in a group of 180 patients with duodenal ulcer and chronic gastritis. In patients with hypersecretion the medication with bishpan and inderal as compared with atropine caused considerable shifts in the indices of gastric secretion. Isoproterenol exerted a stimulating influence both on initial hyper- and hyposecretion, while the other preparations studied were shown not to cause any essential rise in gastric secretion in patients with secretory deficiency. Reliable changes of the stimulated gastric secretion were observed only after inderal. The data obtained can be useful when choosing a rational method for the therapy of gastric scretory disorders.
对180例十二指肠溃疡和慢性胃炎患者进行了研究,观察了给予不同制剂后胃分泌的变化。与阿托品相比,在分泌过多的患者中,使用比沙潘和普萘洛尔进行药物治疗可使胃分泌指标发生显著变化。异丙肾上腺素对初始分泌过多和分泌过少均有刺激作用,而所研究的其他制剂在分泌不足的患者中未显示出可导致胃分泌显著增加。仅在使用普萘洛尔后观察到刺激胃分泌有可靠变化。所获得的数据在选择合理的胃分泌紊乱治疗方法时可能有用。