乳腺导管内乳头状瘤 18F-FDG PET/CT 高摄取一例

A Case of Intraductal Papilloma of the Breast With High 18F-FDG Uptake on PET/CT.

机构信息

From the *Department of Radiology, Nanpuh Hospital, Kagoshima, Japan; Departments of †Radiology, and ‡Human Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

出版信息

Clin Nucl Med. 2015 Nov;40(11):905-7. doi: 10.1097/RLU.0000000000000873.

DOI:10.1097/RLU.0000000000000873

PMID:26164173

Abstract

We present a case of intraductal papilloma in the right breast of a 51-year-old woman with high F-FDG uptake. Its maximum standardized uptake value increased from 10.2 on early (1 h) PET/CT scan to 12.2 on delayed (2 h) PET/CT scan suggesting a primary breast cancer. However, histopathology proved it to be an intraductal papilloma. Immunohistochemically, strong expression of glucose transporter-1 and weak expression of hexokinase-II were noted in the papilloma. With the detection of a subareolar intracystic mass with high F-FDG uptake, intraductal papilloma should be included in the differential diagnosis.

摘要

我们报告了一例 51 岁女性右乳内导管乳头状瘤病例，其 F-FDG 摄取较高。其最大标准化摄取值从早期（1 小时）PET/CT 扫描的 10.2 增加到延迟（2 小时）PET/CT 扫描的 12.2，提示为原发性乳腺癌。然而，组织病理学证实为导管内乳头状瘤。免疫组化显示，在乳头状瘤中葡萄糖转运蛋白-1 表达较强，己糖激酶-Ⅱ表达较弱。随着乳晕下腔内囊性肿块高 F-FDG 摄取的检测，应将导管内乳头状瘤纳入鉴别诊断。