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阿米替林过量服用并发肠道假性梗阻和盲肠穿孔。

Amitriptyline overdose complicated by intestinal pseudo-obstruction and caecal perforation.

作者信息

McMahon A J

机构信息

Department of General Surgery, Southern General Hospital, Glasgow, UK.

出版信息

Postgrad Med J. 1989 Dec;65(770):948-9. doi: 10.1136/pgmj.65.770.948.

DOI:10.1136/pgmj.65.770.948
PMID:2616439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2429560/
Abstract

I report a case of intestinal pseudo-obstruction, spontaneous caecal perforation and faecal peritonitis caused by an overdose of amitriptyline. This rare but serious complication should be borne in mind in patients who remain constipated while convalescing after self-poisoning with tricyclic antidepressants.

摘要

我报告一例因过量服用阿米替林导致的肠道假性梗阻、自发性盲肠穿孔和粪性腹膜炎病例。对于在三环类抗抑郁药自我中毒康复期间仍便秘的患者,应牢记这种罕见但严重的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15e1/2429560/c51c1d40a67f/postmedj00180-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15e1/2429560/c51c1d40a67f/postmedj00180-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15e1/2429560/c51c1d40a67f/postmedj00180-0083-a.jpg

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本文引用的文献

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Adynamic ileus and nortriptyline.无动力性肠梗阻与去甲替林
Br Med J. 1966 Apr 2;1(5491):841-2. doi: 10.1136/bmj.1.5491.841.
2
ADYNAMIC ILEUS AND AMITRIPTYLINE: THREE CASE REPORTS.动力性肠梗阻与阿米替林:三例病例报告
Med J Aust. 1964 Jun 13;1:921-2. doi: 10.5694/j.1326-5377.1964.tb114431.x.
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Ileus after amitriptyline.阿米替林所致肠梗阻
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Acute on chronic intestinal pseudoobstruction responds to neostigmine.新斯的明可治疗慢性肠梗阻急性发作。
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Constipation and colonic perforation complicating calcium resonium therapy.钙聚苯乙烯磺酸钠治疗并发便秘和结肠穿孔
Postgrad Med J. 1992 Apr;68(798):302. doi: 10.1136/pgmj.68.798.302.
Br Med J. 1963 Apr 27;1(5338):1160. doi: 10.1136/bmj.1.5338.1160.
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Pseudo-obstruction of the colon (Ogilvie's syndrome).结肠假性梗阻(奥吉尔维综合征)。
Dis Colon Rectum. 1980 Mar;23(2):106-8. doi: 10.1007/BF02587606.
5
Colonoscopic decompression and intubation of the cecum for Ogilvie's syndrome.结肠镜减压及盲肠插管治疗奥吉尔维综合征
Dis Colon Rectum. 1983 Aug;26(8):503-6. doi: 10.1007/BF02563739.
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Acute self-poisoning with tricyclic antidepressants in 295 consecutive patients treated in an ICU.
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The colon in the pseudoobstructive syndrome.假性肠梗阻综合征中的结肠
Clin Gastroenterol. 1986 Oct;15(4):745-62.
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Changing pattern of drugs used for self-poisoning.用于自我中毒的药物使用模式的变化。
Br Med J. 1978 Jan 14;1(6105):90-3. doi: 10.1136/bmj.1.6105.90.
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Intestinal pseudo-obstruction.肠道假性梗阻
Med J Aust. 1979 Oct 6;2(7):339-41.