Anuras S, Baker C R
Clin Gastroenterol. 1986 Oct;15(4):745-62.
Colonic pseudoobstruction can occur as part of a generalized chronic intestinal pseudoobstruction syndrome or as an isolated entity. Isolated colonic pseudoobstruction can occur in two unrelated forms: the acute and chronic forms. Acute colonic pseudoobstruction is frequently a hospital-acquired disease that arises as a complication of other illnesses. The syndrome must be recognized and treated with early colonoscopic decompression to prevent cecal or colonic perforation. Chronic colonic pseudoobstruction is a syndrome of many causes. The prognosis of patients with chronic colonic pseudoobstruction is much better than that of generalized chronic intestinal pseudoobstruction, because the patients become asymptomatic with appropriate operations. The pathogenesis of acute colonic pseudoobstruction and several types of chronic colonic pseudoobstruction is not known. Further investigations should include bacteriologic study, histopathologic studies (examinations of smooth muscle and myenteric plexus), and examination of extrinsic nerves of the colon. With these approaches, a better understanding of the pathogenesis of these syndromes will be achieved.
结肠假性梗阻可作为全身性慢性肠道假性梗阻综合征的一部分出现，也可作为一个孤立的病症出现。孤立性结肠假性梗阻可表现为两种不相关的形式：急性和慢性形式。急性结肠假性梗阻通常是一种医院获得性疾病，作为其他疾病的并发症出现。必须认识到该综合征并早期行结肠镜减压治疗，以防止盲肠或结肠穿孔。慢性结肠假性梗阻是一种由多种原因引起的综合征。慢性结肠假性梗阻患者的预后比全身性慢性肠道假性梗阻患者好得多，因为通过适当的手术患者可无症状。急性结肠假性梗阻和几种类型的慢性结肠假性梗阻的发病机制尚不清楚。进一步的研究应包括细菌学研究、组织病理学研究（平滑肌和肠肌丛检查）以及结肠外在神经检查。通过这些方法，将能更好地理解这些综合征的发病机制。
