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用于肺泡蛋白沉积症的治疗性全肺灌洗:操作更新

Therapeutic Whole-Lung Lavage for Pulmonary Alveolar Proteinosis: A Procedural Update.

作者信息

Abdelmalak Basem B, Khanna Ashish K, Culver Daniel A, Popovich Marc J

机构信息

Departments of *General Anesthesiology and Outcomes Research †Critical Care Anesthesiology, Anesthesiology Institute ‡Respiratory Institute, Cleveland Clinic, Cleveland, OH.

出版信息

J Bronchology Interv Pulmonol. 2015 Jul;22(3):251-8. doi: 10.1097/LBR.0000000000000180.

Abstract

Pulmonary alveolar proteinosis is a disease caused by increased accumulation and impaired clearance of surfactant by alveolar macrophages. This narrative review summarizes the role of therapeutic whole-lung lavage in the management of pulmonary alveolar proteinosis. We describe the preprocedural evaluation, indications, and anesthetic considerations, along with step-by step technical aspects of the procedure, postoperative recovery, potential complications, and long-term outcomes.

摘要

肺泡蛋白沉积症是一种由于肺泡巨噬细胞对表面活性物质的清除功能受损且蓄积增加所引起的疾病。本叙述性综述总结了治疗性全肺灌洗在肺泡蛋白沉积症管理中的作用。我们描述了术前评估、适应证、麻醉注意事项,以及该操作的逐步技术要点、术后恢复情况、潜在并发症和长期预后。

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