脑静脉窦血栓形成的临床特征
Clinical characteristics of cerebral venous sinus thrombosis.
作者信息
Wang Jia-Wei, Li Jin-Ping, Song Ying-Lun, Tan Ke, Wang Yu, Li Tao, Guo Peng, Li Xiong, Wang Yan, Zhao Qi-Huang
机构信息
Department of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, P. R. China.
出版信息
Neurosciences (Riyadh). 2015 Jul;20(3):292-5. doi: 10.17712/nsj.2015.3.20140625.
OBJECTIVE
To investigate the risk factors, clinical presentation, neuroimaging features, treatment, and prognosis of patients with cerebral venous sinus thrombosis (CVST).
METHODS
We retrospectively analyzed the data of 19 patients with a diagnosis of CVST admitted to Beijing Chao-Yang Hospital affiliated to Capital Medical University, Beijing, China between January 2010 and December 2013.
RESULTS
There were 9 men and 10 women (age range: 27-75 years). Headache (84.2%) and focal signs (57.9%) were the 2 most common symptoms. Direct evidence of thrombosis was found on CT in 42.1%, and on MRI in 52.6%. Two or more sinuses were involved in 78.9% of cases, in which the transverse sinus plus sigmoid sinus were the most commonly involved combination. All patients received anticoagulant therapy. Most patients (84.2%) had no neurological sequelae at discharge, and only 3 patients (15.8%) recovered with sequelae.
CONCLUSION
Our study provides detailed information on the clinical manifestations, neuroimages, management, outcome, and risk factors of the patients with CVST.
目的
探讨脑静脉窦血栓形成（CVST）患者的危险因素、临床表现、神经影像学特征、治疗方法及预后。
方法
回顾性分析2010年1月至2013年12月在中国北京首都医科大学附属北京朝阳医院收治的19例CVST确诊患者的数据。
结果
男性9例，女性10例（年龄范围：27 - 75岁）。头痛（84.2%）和局灶性体征（57.9%）是最常见的两种症状。CT发现血栓直接证据的占42.1%，MRI发现的占52.6%。78.9%的病例累及两个或更多静脉窦，其中横窦加乙状窦是最常受累的组合。所有患者均接受抗凝治疗。大多数患者（84.2%）出院时无神经后遗症，仅3例患者（15.8%）康复后有后遗症。
结论
我们的研究提供了有关CVST患者临床表现、神经影像学、治疗、结局及危险因素的详细信息。
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