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巴氏涂片与醋酸肉眼观察法(VIA)在筛查宫颈上皮内瘤变(CIN)和早期宫颈癌中的对比研究。

Comparative study between pap smear and visual inspection with acetic acid (via) in screening of CIN and early cervical cancer.

作者信息

Bhattacharyya Ashish Kumar, Nath Jyan Dip, Deka Harajyoti

机构信息

Department of Obstetrics and Gynaecology, Gauhati Medical College and Hospital, Guwahati, Assam, India.

出版信息

J Midlife Health. 2015 Apr-Jun;6(2):53-8. doi: 10.4103/0976-7800.158942.

Abstract

BACKGROUND

Cervical cancer is the second most common among women globally. In most cases of Assam, Ca Cervix is detected late due to lack of effective screening programme.

AIM

To screen the patient at Gynaecology OPD at the age 18-60 yrs by doing pap smear, VIA (Visual Inspection with Acetic Acid) and to detect sensitivity and specificity for detecting CIN and early Ca Cervix.

MATERIAL AND METHOD

It is a cross sectional study of 300 women (18- 60 yrs) who fulfill selection criteria. The pap smear and VIA are done in these cases. In positive cases, cervical biopsy and histopathological studies are done, The sensitivity and specificity of each test are determined and compared.

RESULT AND OBSERVATION

The positive result detected from cytology are 22, VIA was positive in 52 cases. The histology of 19 cases are suggestive of CIN and Ca Cervix.

DISCUSSION

The findings were compared with other studies and evaluated.

SUMMARY

The most common finding in per speculum examination is cervical erosion. The sensitivity of VIA is 89% (versus pap smear-52%) the specificity of VIA is 87% (versus pap smear-95%). The accuracy VIA is 87% compared to pap smear-93%.

CONCLUSION

The lack of effective and implementable screening programme lead to reporting of advanced cases of Ca Cervix. If detected at CIN or early Ca cervix stage, effective treatment can be provided with encouraging results. Therefore effective & implementable Ca Cervix screening need to be provided in our country.

摘要

背景

宫颈癌是全球女性中第二常见的癌症。在阿萨姆邦的大多数病例中,由于缺乏有效的筛查计划,宫颈癌被发现时已处于晚期。

目的

通过进行巴氏涂片检查、醋酸肉眼观察法(VIA)对18至60岁妇科门诊患者进行筛查,并检测检测宫颈上皮内瘤变(CIN)和早期宫颈癌的敏感性和特异性。

材料与方法

这是一项对300名符合入选标准的18至60岁女性进行的横断面研究。对这些病例进行巴氏涂片检查和VIA检查。对阳性病例进行宫颈活检和组织病理学研究,确定并比较每项检查的敏感性和特异性。

结果与观察

细胞学检查阳性结果为22例,VIA检查阳性52例。19例组织学检查提示为CIN和宫颈癌。

讨论

将研究结果与其他研究进行比较并评估。

总结

在窥器检查中最常见的发现是宫颈糜烂。VIA的敏感性为89%(相比之下巴氏涂片为52%),VIA的特异性为87%(相比之下巴氏涂片为95%)。与巴氏涂片的93%相比,VIA的准确率为87%。

结论

缺乏有效且可实施的筛查计划导致晚期宫颈癌病例的报告。如果在CIN或早期宫颈癌阶段被发现,可以提供有效的治疗并取得令人鼓舞的结果。因此,我国需要提供有效且可实施的宫颈癌筛查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a126/4481740/23a365b38065/JMH-6-53-g001.jpg

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