Izzi-Engbeaya Chioma, Salem Victoria, Atkar Rajveer S, Dhillo Waljit S
Section of Investigative Medicine; Imperial College ; London, UK.
Adipocyte. 2014 Nov 14;4(1):1-12. doi: 10.4161/21623945.2014.965609. eCollection 2015 Jan-Mar.
There has been resurgence in interest in brown adipose tissue (BAT) following radiological and histological identification of metabolically active BAT in adult humans. Imaging enables BAT to be studied non-invasively and therefore imaging studies have contributed a significant amount to what is known about BAT function in humans. In this review the current knowledge (derived from imaging studies) about the prevalence, function, activity and regulation of BAT in humans (as well as relevant rodent studies), will be summarized.
在通过放射学和组织学方法鉴定出成年人体内具有代谢活性的棕色脂肪组织(BAT)之后,人们对其的兴趣再度兴起。成像技术能够对BAT进行非侵入性研究,因此成像研究为我们了解BAT在人类中的功能做出了重要贡献。在这篇综述中,将总结目前(来自成像研究)关于BAT在人类中的患病率、功能、活性和调节(以及相关的啮齿动物研究)的知识。