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本文引用的文献

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Presence of brown adipose tissue in an adolescent with severe primary hypothyroidism.一名患有严重原发性甲状腺功能减退症的青少年体内存在棕色脂肪组织。
J Clin Endocrinol Metab. 2014 Sep;99(9):E1686-90. doi: 10.1210/jc.2014-1343. Epub 2014 Jun 10.
2
Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study.与白种高加索人相比,健康瘦的南亚成年人的棕色脂肪组织体积:一项前瞻性、病例对照观察研究。
Lancet Diabetes Endocrinol. 2014 Mar;2(3):210-7. doi: 10.1016/S2213-8587(13)70156-6. Epub 2013 Nov 12.
3
Increased brown adipose tissue oxidative capacity in cold-acclimated humans.冷适应增加人体棕色脂肪组织的氧化能力。
J Clin Endocrinol Metab. 2014 Mar;99(3):E438-46. doi: 10.1210/jc.2013-3901. Epub 2014 Jan 13.
4
Identification of brown adipose tissue using MR imaging in a human adult with histological and immunohistochemical confirmation.利用 MR 成像在一名经组织学和免疫组织化学确认的成年人体内识别棕色脂肪组织。
J Clin Endocrinol Metab. 2014 Jan;99(1):E117-21. doi: 10.1210/jc.2013-2036.
5
The prevalence and predictors of active brown adipose tissue in Chinese adults.中国成年人活跃棕色脂肪组织的流行率及其预测因素。
Eur J Endocrinol. 2014 Feb 4;170(3):359-66. doi: 10.1530/EJE-13-0712. Print 2014 Mar.
6
Body mass index as a determinant of brown adipose tissue function in healthy children.体重指数作为健康儿童棕色脂肪组织功能的决定因素。
J Pediatr. 2014 Feb;164(2):318-22.e1. doi: 10.1016/j.jpeds.2013.10.005. Epub 2013 Nov 14.
7
Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans.棕色脂肪组织对健康人体体脂和葡萄糖代谢的影响。
Int J Obes (Lond). 2014 Jun;38(6):812-7. doi: 10.1038/ijo.2013.206. Epub 2013 Nov 11.
8
Brown adipose tissue quantification in human neonates using water-fat separated MRI.利用水脂分离 MRI 对人类新生儿的棕色脂肪组织进行定量分析。
PLoS One. 2013 Oct 30;8(10):e77907. doi: 10.1371/journal.pone.0077907. eCollection 2013.
9
Hyperthyroidism increases brown fat metabolism in humans.甲状腺功能亢进症增加人类棕色脂肪代谢。
J Clin Endocrinol Metab. 2014 Jan;99(1):E28-35. doi: 10.1210/jc.2013-2312. Epub 2013 Dec 20.
10
Quantification of human and rodent brown adipose tissue function using 99mTc-methoxyisobutylisonitrile SPECT/CT and 18F-FDG PET/CT.使用 99mTc-甲氧基异丁基异腈 SPECT/CT 和 18F-FDG PET/CT 定量人体和啮齿动物棕色脂肪组织功能。
J Nucl Med. 2013 Nov;54(11):1896-901. doi: 10.2967/jnumed.113.121012. Epub 2013 Sep 26.

影像学研究揭示的棕色脂肪组织生理学见解。

Insights into Brown Adipose Tissue Physiology as Revealed by Imaging Studies.

作者信息

Izzi-Engbeaya Chioma, Salem Victoria, Atkar Rajveer S, Dhillo Waljit S

机构信息

Section of Investigative Medicine; Imperial College ; London, UK.

出版信息

Adipocyte. 2014 Nov 14;4(1):1-12. doi: 10.4161/21623945.2014.965609. eCollection 2015 Jan-Mar.

DOI:10.4161/21623945.2014.965609
PMID:26167397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4497292/
Abstract

There has been resurgence in interest in brown adipose tissue (BAT) following radiological and histological identification of metabolically active BAT in adult humans. Imaging enables BAT to be studied non-invasively and therefore imaging studies have contributed a significant amount to what is known about BAT function in humans. In this review the current knowledge (derived from imaging studies) about the prevalence, function, activity and regulation of BAT in humans (as well as relevant rodent studies), will be summarized.

摘要

在通过放射学和组织学方法鉴定出成年人体内具有代谢活性的棕色脂肪组织(BAT)之后,人们对其的兴趣再度兴起。成像技术能够对BAT进行非侵入性研究,因此成像研究为我们了解BAT在人类中的功能做出了重要贡献。在这篇综述中,将总结目前(来自成像研究)关于BAT在人类中的患病率、功能、活性和调节(以及相关的啮齿动物研究)的知识。