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埃塞俄比亚南部与儿童艾滋病毒状况披露相关因素的横断面特征分析

Cross Sectional Characterization of Factors Associated with Pediatric HIV Status Disclosure in Southern Ethiopia.

作者信息

Tadesse Birkneh Tilahun, Foster Byron Alexander, Berhan Yifru

机构信息

Department of Child Health, Hawassa University, College of Health Sciences, Hawassa, Ethiopia.

Department of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.

出版信息

PLoS One. 2015 Jul 13;10(7):e0132691. doi: 10.1371/journal.pone.0132691. eCollection 2015.

Abstract

BACKGROUND

Disclosure of HIV positive status to children and adolescents is a complex process. However, disclosure has been found to be associated with improved outcomes. The objective of the current study was to identify the predictors that facilitate disclosure of HIV status to children and adolescents and to study the reasons for non-disclosure.

METHODS

Interviews of caregivers and reviews of records were done to collect data on caregiver and child information and details regarding the disclosure status of children. Bivariate analysis was done to test the association between HIV status disclosure and different caregiver and child factors. To identify the independent predictors of disclosure, we did multivariable logistic regression.

RESULTS

A total of 177 children attending an HIV clinic were included. The mean age of the participants was 10.1 years (SD = 2.8), and about half (50.8%) were female. Most caregivers, 137 (77.8%) stated that disclosure of HIV status to children is important and should be done. However, disclosure had only been made to 59 (33.3%) of the participants. Child age more than 10 years [AOR = 6.7; 95%CI: 1.73-26.01], duration of HIV diagnosis of 5 years or more [AOR = 4.4; 95%CI: 1.26-15.06] and taking a zidovudin (AZT) based regimen [AOR = 3.5; 95%CI: 1.31-9.53] predicted HIV positive status disclosure. Additionally, length of treatment of caregivers of more than 14 years [AOR = 3.9; 95%CI: 1.07-14.61], disclosure of caregiver's HIV status to children and/or others [AOR = 4.7; 95%CI: 1.19-18.74], and the child's inquiry about their condition [AOR = 4.5; 95%CI: 1.16-17.43] increased the odds of disclosure.

CONCLUSION

The rate of disclosure among HIV infected children in southern Ethiopia is low. Primarily time-based factors were associated with the probability of HIV positive status disclosure and a specific regimen which has not been found previously. Further qualitative research may elucidate more on these factors; educational strategies may address some of these determinants.

摘要

背景

向儿童和青少年披露艾滋病毒阳性状况是一个复杂的过程。然而,研究发现披露与更好的结果相关。本研究的目的是确定促进向儿童和青少年披露艾滋病毒状况的预测因素,并研究不披露的原因。

方法

对照顾者进行访谈并查阅记录,以收集关于照顾者和儿童的信息以及有关儿童披露状况的详细信息。进行双变量分析以检验艾滋病毒状况披露与不同照顾者和儿童因素之间的关联。为了确定披露的独立预测因素,我们进行了多变量逻辑回归分析。

结果

总共纳入了177名在艾滋病毒诊所就诊的儿童。参与者的平均年龄为10.1岁(标准差=2.8),约一半(50.8%)为女性。大多数照顾者,137名(77.8%)表示向儿童披露艾滋病毒状况很重要且应该进行。然而,仅向59名(33.3%)参与者进行了披露。10岁以上儿童[AOR=6.7;95%置信区间:1.73 - 26.01]、艾滋病毒诊断持续时间5年或更长时间[AOR=4.4;95%置信区间:1.26 - 15.06]以及采用基于齐多夫定(AZT)的治疗方案[AOR=3.5;95%置信区间:1.31 - 9.53]可预测艾滋病毒阳性状况的披露。此外,照顾者治疗时长超过14年[AOR=3.9;95%置信区间:1.07 - 14.61]、照顾者向儿童和/或其他人披露自己的艾滋病毒状况[AOR=4.7;95%置信区间:1.19 - 18.74]以及儿童询问自己的病情[AOR=4.5;95%置信区间:1.16 - 17.43]会增加披露的几率。

结论

埃塞俄比亚南部艾滋病毒感染儿童的披露率较低。主要是基于时间的因素与艾滋病毒阳性状况披露的可能性相关,以及一种以前未发现的特定治疗方案。进一步的定性研究可能会更清楚地阐明这些因素;教育策略可能会解决其中一些决定因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c03/4500496/0fba09f83d79/pone.0132691.g001.jpg

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