Department of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Amhara, Ethiopia.
Department of Community Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Amhara, Ethiopia.
PeerJ. 2022 Aug 23;10:e13896. doi: 10.7717/peerj.13896. eCollection 2022.
HIV-positive status disclosure for children is challenging for family members, guardians, and healthcare professionals. Disclosure is very challenging, particularly for children, yet no systematic synthesis of evidence accurately measures HIV-positive status disclosure in children. This systematic review and meta-analysis study aimed to quantify the national prevalence of pediatric HIV-positive status disclosure in Ethiopia and identify factors associated with HIV-positive status disclosure.
We systematically searched PubMed, EMBASE, Web of Science databases, and google scholar for relevant published studies. Studies published in the English language and conducted with cohort, case-control, and cross-sectional designs were eligible for the review. The primary and secondary outcomes of the study were HIV-positive status disclosure and factors associated with HIV-positive status disclosure, respectively. The quality of the included studies was assessed using the Joanna Briggs Institute critical appraisal tools. A random effect- model was used to estimate the pooled prevalence of HIV-positive status disclosure. Heterogeneity and publication bias of included studies was determined using I and Egger's test, respectively.
From 601 records screened, nine relevant studies consisting of 2,442 HIV-positive children were included in the analysis. The overall pooled prevalence of HIV-positive status disclosure among children living with HIV/AIDS in Ethiopia was 31.2% (95% CI [23.9-38.5]). HIV-negative status of caregivers (AOR: 2.01; 95% CI [1.28-3.18]), long duration on ART (greater than 5 years) (AOR: 3.2; 95% CI [1.77-5.78]) and older age of the child (>10 years) (AOR: 7.2; 95% CI [4.37-11.88]) were significantly associated with HIV-positive status disclosure.
Low prevalence of pediatric HIV-positive status disclosure was observed in Ethiopia. The longer duration of ART, the HIV-negative status of the caregiver, and older age greater than 10 years were the predictors of pediatric HIV-positive status disclosure. Health system leaders and policymakers shall design training and counseling programs for healthcare professionals and caregivers to enhance their awareness about HIV-positive status disclosure.
This review was registered under PROSPERO and received a unique registration number, CRD42019119049.
对于家庭成员、监护人以及医疗保健专业人员来说，向儿童披露艾滋病毒阳性状况具有挑战性。披露对于儿童来说非常具有挑战性，但目前还没有系统的综合证据来准确衡量儿童的艾滋病毒阳性状况披露情况。本系统评价和荟萃分析旨在量化埃塞俄比亚儿童艾滋病毒阳性状况披露的全国流行率，并确定与艾滋病毒阳性状况披露相关的因素。
我们系统地检索了 PubMed、EMBASE、Web of Science 数据库和谷歌学术，以获取相关的已发表研究。符合审查标准的研究为发表在英语语言并采用队列、病例对照和横断面设计的研究。研究的主要和次要结果分别为艾滋病毒阳性状况披露和与艾滋病毒阳性状况披露相关的因素。使用 Joanna Briggs 研究所的批判性评估工具评估纳入研究的质量。使用随机效应模型估计艾滋病毒阳性状况披露的汇总流行率。使用 I 检验和 Egger 检验分别确定纳入研究的异质性和发表偏倚。
从筛选出的 601 条记录中，有 9 项相关研究共纳入了 2442 名艾滋病毒阳性儿童。埃塞俄比亚艾滋病毒感染者儿童的艾滋病毒阳性状况披露总体汇总流行率为 31.2%（95%CI[23.9-38.5]）。照顾者的艾滋病毒阴性状况（AOR：2.01；95%CI[1.28-3.18]）、抗逆转录病毒治疗时间较长（大于 5 年）（AOR：3.2；95%CI[1.77-5.78]）和儿童年龄较大（大于 10 岁）（AOR：7.2；95%CI[4.37-11.88]）与艾滋病毒阳性状况披露显著相关。
埃塞俄比亚儿童艾滋病毒阳性状况披露的流行率较低。抗逆转录病毒治疗时间较长、照顾者艾滋病毒阴性状况以及年龄大于 10 岁是儿童艾滋病毒阳性状况披露的预测因素。卫生系统领导者和政策制定者应设计针对医疗保健专业人员和照顾者的培训和咨询计划，以提高他们对艾滋病毒阳性状况披露的认识。
本综述在 PROSPERO 下注册，并获得了独特的注册号 CRD42019119049。
