Zong Shuang-Le, Kan Shi-Lian, Su Li-Xin, Wang Bin
Department of Orthopedics Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China.
Department of Orthopedics Institute, The Second Hospital of Tangshan, Tangshan, 063000, Hebei Province, People's Republic of China.
J Orthop Surg Res. 2015 Jul 15;10:108. doi: 10.1186/s13018-015-0252-2.
Dorsally displaced distal radius fractures (DDDRF) are frequent injuries in clinical practice. Traditional percutaneous Kirschner wires (K-wire) and open reduction with volar locking plate (VLP) are the two most common surgical fixation techniques used to manage DDDRF. However, there is no current consensual evidence to guide the selection of one technique over the other. Therefore, we undertook a systematic search and meta-analysis to compare clinical outcomes and complications of these two treatment approaches for DDDRF.
The following electronic databases were searched by two independent reviewers, up to April 2015: PubMed, ScienceDirect and Wiley Online Library. High-quality randomized controlled trials (RCTs) comparing VLP and percutaneous K-wire fixation for DDDRF were identified. Pooled mean differences were calculated for the following continuous outcome variables: disabilities of the arm, shoulder and hand (DASH) score, grip strength and wrist range of motion. Pooled odds ratios were calculated for rates of total postoperative complications, including superficial infection, deep infection, complex regional pain syndrome (CRPS), carpal tunnel syndrome (CTS), neurological injury, tendon rupture, tenosynovitis, loss of reduction and additional surgery to remove hardware. The meta-analysis was completed using RevMan 5.3 software.
Seven RCTs, with a total of 875 patients, were included in our meta-analysis. Open reduction internal fixation (ORIF) with VLP fixation provided statistically lower DASH scores, reduced the incidence of total postoperative complications and specifically lowered the rate of superficial infection, when compared, over a 1-year follow-up, to percutaneous K-wire fixation. VLP fixation also provided significantly better grip strength and range of wrist flexion and supination in the early 6-month postoperative period, compared with percutaneous K-wire fixation.
ORIF with VLP fixation provided lower DASH scores and reduced total postoperative complications, most specifically lowering the risk for postoperative superficial infection compared to K-wire fixation over a 1-year follow-up period. However, superficial pin track infections do not cause clinical debility in the vast majority of cases. Thus, the claim of reduced superficial infection rate may not be clinically important. The only reasonable conclusion that can be drawn is that at present, there is insufficient data even on our meta-analysis to help the clinician make an informed choice.
桡骨远端背侧移位骨折(DDDRF)是临床实践中常见的损伤。传统的经皮克氏针(K 针)和掌侧锁定钢板切开复位内固定(VLP)是治疗 DDDRF 最常用的两种手术固定技术。然而,目前尚无共识性证据指导选择其中一种技术而非另一种。因此,我们进行了系统检索和荟萃分析,以比较这两种治疗 DDDRF 方法的临床疗效和并发症。
由两名独立审阅者检索以下电子数据库,截至 2015 年 4 月:PubMed、ScienceDirect 和 Wiley Online Library。确定了比较 VLP 和经皮 K 针固定治疗 DDDRF 的高质量随机对照试验(RCT)。计算以下连续结局变量的合并平均差:手臂、肩部和手部功能障碍(DASH)评分、握力和腕关节活动范围。计算术后总并发症发生率的合并比值比,包括浅表感染、深部感染、复杂性区域疼痛综合征(CRPS)、腕管综合征(CTS)、神经损伤、肌腱断裂、腱鞘炎、复位丢失和取出内固定物的二次手术。使用 RevMan 5.3 软件完成荟萃分析。
我们的荟萃分析纳入了 7 项 RCT,共 875 例患者。与经皮 K 针固定相比,在 1 年的随访中,VLP 切开复位内固定(ORIF)在统计学上降低了 DASH 评分,降低了术后总并发症发生率,尤其是降低了浅表感染率。与经皮 K 针固定相比,VLP 固定在术后 6 个月早期也提供了明显更好的握力以及腕关节屈曲和旋后范围。
在 1 年的随访期内,与 K 针固定相比,VLP 切开复位内固定降低了 DASH 评分,减少了术后总并发症,最显著降低了术后浅表感染风险。然而,在绝大多数情况下,浅表针道感染不会导致临床功能障碍。因此,浅表感染率降低这一说法可能在临床上并不重要。唯一合理的结论是,目前即使是我们的荟萃分析也没有足够的数据来帮助临床医生做出明智的选择。