Yang Xiao, Jiang Qingjun, Yu Bingbing
Department of Medical Imaging, Jinan Military General Hospital, Jinan, Shandong 250031, P.R. China.
Oncol Lett. 2015 Jul;10(1):354-358. doi: 10.3892/ol.2015.3162. Epub 2015 Apr 29.
Solitary fibrous tumors (SFTs) of the sella turcica are rare entities, with only four cases reported in the literature thus far. The current study describes two cases of SFT arising from the sella turcica, including presentation of the clinical, imaging and histopathological findings, and the initial treatment strategies and diagnosis, with emphasis on the treatment of the tumor in this unusual location. Magnetic resonance imaging is a useful method for identifying a solid or heterogeneous mass; however, histopathological and immunohistochemical data are required to clarify such diagnoses. The majority of SFTs exhibit clinically benign behavior and have a positive outcome; however, certain SFTs may present malignant features. Although gross total resection of SFTs in the sella turcica is important, subtotal resection with subsequent stereotactic radiotherapy is proposed as an acceptable alternative. Furthermore, careful and long-term follow-up of patients with SFT of the sella turcica is required as the clinical outcome is unpredictable.
蝶鞍区孤立性纤维瘤(SFTs)是罕见的疾病,迄今为止文献中仅报道了4例。本研究描述了2例起源于蝶鞍区的SFTs,包括临床、影像学和组织病理学表现,以及初始治疗策略和诊断,重点是该特殊部位肿瘤的治疗。磁共振成像(MRI)是识别实性或异质性肿块的有用方法;然而,需要组织病理学和免疫组化数据来明确此类诊断。大多数SFTs表现出临床良性行为且预后良好;然而,某些SFTs可能呈现恶性特征。虽然蝶鞍区SFTs的全切除很重要,但建议行次全切除并随后进行立体定向放射治疗作为一种可接受的替代方案。此外,由于临床结果不可预测,蝶鞍区SFTs患者需要仔细且长期的随访。