Ong Ken K, Kennedy Kathy, Castañeda-Gutiérrez Eurídice, Forsyth Stewart, Godfrey Keith M, Koletzko Berthold, Latulippe Marie E, Ozanne Susan E, Rueda Ricardo, Schoemaker Marieke H, van der Beek Eline M, van Buuren Stef, Fewtrell Mary
MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Institute of Child Health, UCL, London, UK.
Acta Paediatr. 2015 Oct;104(10):974-86. doi: 10.1111/apa.13128.
In preterm infants, poor postnatal growth is associated with adverse neurocognitive outcomes; conversely, rapid postnatal growth is supposedly harmful for future development of metabolic diseases.
In this systematic review, observational studies reported consistent positive associations between postnatal weight or head growth and neurocognitive outcomes; however, there was limited evidence from the few intervention studies. Evidence linking postnatal weight gain to later adiposity and other cardiovascular disease risk factors in preterm infants was also limited.
在早产儿中,出生后生长不良与不良神经认知结局相关;相反,出生后快速生长被认为对代谢性疾病的未来发展有害。
在本系统评价中,观察性研究报告了出生体重或头围生长与神经认知结局之间一致的正相关;然而,少数干预研究的证据有限。将早产儿出生后体重增加与后期肥胖及其他心血管疾病风险因素联系起来的证据也很有限。