Simony Ane, Hansen Emil Jesper, Carreon Leah Y, Christensen Steen Bach, Andersen Mikkel Osterheden
Sector for Spine Surgery & Research, Middelfart Hospital Denmark, Ostre Hougvej 55, 5500 Middelfart, DK Denmark.
Scoliosis. 2015 Jul 16;10:22. doi: 10.1186/s13013-015-0045-8. eCollection 2015.
Since 1962 to the mid eighties the Harrington Rod instrumentation was the Golden standard for surgical treatment of Adolescent Idiopathic Scoliosis (AIS). The Boston braces were introduced in the 1970´s and are still used as a conservative treatment, for curves less than 40°. Very few long-term studies exists, focusing on the health related quality of life. The purpose of this study was to evaluate the long-term health related outcome, in a cohort of AIS patients, treated 25 years ago.
219 consecutive patients treated with Boston brace (Brace) or posterior spinal fusion (PSF) using Harrington- DDT instrumentation between 1983 and 1990 at Rigshospitalet Copenhagen, were invited to participate in a long-term evaluation study. A validated Danish version of the Scoliosis Research Society 22R (SRS22R) and Short Form-36 (SF36v1) were administrated to the patients two weeks before the clinical and radiological examination.
159 (72,6 %) patients participated in the clinical follow up and questionnaires, 11 patients participated only in the questionnaires, 8 emigrated, 4 were excluded due to progressive neurological disease and 2 were deceased. The total follow up was 170 patients (83 %), and the average follow up was 24.5 years (22-30 years). SRS22R domain scores were within the range described as normal for the general population with no statistical difference between the groups except in the Satisfaction domain, where the PSF group had better scores than the braced group. The SF36 PCS and MCS scores in both AIS cohorts were similar to the scores for the general population.
HRQOLs, as measured by the SRS22R and SF-36, of adult AIS patients treated with Boston brace or PSF during adolescence were similar to the general population. No clinical progression of the deformity has been detected during the 25-year follow up period. The PSF group had a small but statistically significant higher score in the Satisfaction domain compared to the braced group.
S-20110025 Regional Committees on Health Research Ethics for Southern Denmark.
从1962年到八十年代中期,哈灵顿棒器械是青少年特发性脊柱侧凸(AIS)手术治疗的金标准。波士顿支具于20世纪70年代问世,目前仍用于对小于40°的侧弯进行保守治疗。很少有长期研究关注与健康相关的生活质量。本研究的目的是评估25年前接受治疗的一组AIS患者与健康相关的长期结局。
邀请1983年至1990年间在哥本哈根里格霍斯皮塔尔使用哈灵顿-DDT器械接受波士顿支具(支具)或后路脊柱融合术(PSF)治疗的219例连续患者参与一项长期评估研究。在临床和放射学检查前两周,向患者发放经过验证的丹麦版脊柱侧凸研究学会22R问卷(SRS22R)和简短健康调查问卷36项简表(SF36v1)。
159例(72.6%)患者参与了临床随访和问卷调查,11例患者仅参与了问卷调查,8例移民,4例因进行性神经疾病被排除,2例死亡。总随访人数为170例患者(83%),平均随访时间为24.5年(22 - 30年)。SRS22R领域得分在一般人群正常范围内,除满意度领域外,两组之间无统计学差异,PSF组在该领域得分高于支具组。两个AIS队列中的SF36生理健康综合评分(PCS)和心理健康综合评分(MCS)与一般人群得分相似。
青少年时期接受波士顿支具或PSF治疗的成年AIS患者,通过SRS22R和SF - 36测量的健康相关生活质量与一般人群相似。在25年的随访期内未发现畸形的临床进展。与支具组相比,PSF组在满意度领域的得分略高,但具有统计学意义。
丹麦南部卫生研究伦理区域委员会S - 20110025