Dovzhanskiĭ S I, Orkin V F, Myshkina A K, Pavlenko L B
Vestn Dermatol Venerol. 1989(11):41-5.
Clinical and laboratory examinations of 250 patients with chronic dermatoses (eczema, neurodermatitis, psoriasis, pemphigus, etc.) have revealed secondary candidal involvement of the skin and mucosa in 121 (46.6%). C. albicans, often associated with bacillary (33.3%) or bacterial (7.3%) microflora, predominated among the yeast-like fungi isolated from the patients. These data point to the necessity of prescribing, besides the antimycotic agents, a complex of pathogenetic therapy including immunomodulators, in order to cut down the terms of treatment and prevent secondary candidal infection in the patients with chronic dermatoses.
对250例慢性皮肤病(湿疹、神经性皮炎、银屑病、天疱疮等)患者进行的临床和实验室检查发现,121例(46.6%)患者的皮肤和黏膜存在继发性念珠菌感染。白色念珠菌在从患者分离出的酵母样真菌中占主导地位,常与杆菌(33.3%)或细菌(7.3%)菌群相关。这些数据表明,除抗真菌药物外,还需开具包括免疫调节剂在内的综合病因治疗方案,以缩短治疗时间并预防慢性皮肤病患者的继发性念珠菌感染。