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[内脏念珠菌病患者内分泌与免疫系统的功能特征]

[Functional characteristics of the endocrine and immune systems in patients with visceral candidiasis].

作者信息

Sokolova G A, Karaev Z O, Sil'nitskiĭ P A, Sardyko N V, Ivanova L A

出版信息

Ter Arkh. 1989;61(11):81-5.

PMID:2633397
Abstract

A study was made of pituitary, thyroid, parathyroid, endocrine pancreatic, adrenocortical and immune system functions in 56 patients afflicted with visceral candidiasis. The clinical and laboratory data obtained point to the presence in some patients with visceral candidiasis of parathyroid, thyroid, pancreatic and adrenocortical dysfunctions, attesting to their importance in the disease pathogenesis. The role of immune disorders, particularly that of the T component of the immunity system is found to be of paramount importance as well in the pathogenesis of candidiasis. Correction of endocrine disorders coupled with antimycotic therapy brought about a more rapid and steadier therapeutic effect.

摘要

对56例内脏念珠菌病患者的垂体、甲状腺、甲状旁腺、内分泌胰腺、肾上腺皮质和免疫系统功能进行了研究。所获得的临床和实验室数据表明,一些内脏念珠菌病患者存在甲状旁腺、甲状腺、胰腺和肾上腺皮质功能障碍,证明了它们在疾病发病机制中的重要性。免疫紊乱的作用,尤其是免疫系统T成分的作用,在念珠菌病的发病机制中也被发现至关重要。纠正内分泌紊乱并结合抗真菌治疗带来了更快、更稳定的治疗效果。

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