Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, Illinois.
Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MBP-0014-2014.
For a generation of microbiologists who study pathogenesis in the context of the human microbiome, understanding the diversity of bacterial metabolism is essential. In this chapter, I briefly describe how and why I became, and remain, interested in metabolism. I then will describe and compare some of the strategies used by bacteria to consume sugars as one example of metabolic diversity. I will end with a plea to embrace metabolism in the endeavor to understand pathogenesis.
对于研究人类微生物组背景下发病机制的一代微生物学家来说，了解细菌代谢的多样性至关重要。在本章中，我将简要描述我是如何以及为何对代谢产生兴趣，并一直保持兴趣。然后，我将描述和比较细菌用来消耗糖的一些策略，以此作为代谢多样性的一个例子。最后，我将呼吁在努力理解发病机制的过程中接受代谢。
