Carbone Iacopo, Childs Helene, Aljizeeri Ahmed, Merchant Naeem, Friedrich Matthias G
CMR Centre, Montreal Heart Institute, University of Montreal, Montreal, QC, Canada H1T 1C8 ; Department of Radiological, Onchological and Pathological Sciences, Sapienza, University of Rome, 00161 Rome, Italy ; Stephenson CMR Centre, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, AB, Canada T2N 2T9.
Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4.
Biomed Res Int. 2015;2015:232649. doi: 10.1155/2015/232649. Epub 2015 Jun 21.
The purpose of our study was to identify the suitability of various skeletal muscles as reference regions for calculating the T2 SI ratio for a semiautomated quantification of the extent of myocardial edema with T2-weighted images.
Thirty-four patients with acute myocardial infarction (MI) were enrolled. The extent of myocardial edema was determined by T2 SI ratio map, using 4 different muscles as reference: major and minor pectoralis, serratus anterior, teres minor-infraspinatus, and subscapularis. The size of myocardial edema as visually quantified was used as the standard of truth. The control group consisted of 15 patients with chronic MI. Intra- and interobserver variability were assessed.
Due to poor image quality four patients were excluded from the analysis. In acute MI patients, serratus anterior muscle showed the strongest correlation with the visual analysis (r = 0.799; P < 0.001) and low inter- and intraobserver variability, while the other muscles resulted in a significant interobserver variability. In contrast, the use of other muscles as a reference led to overestimating edema size.
In acute MI patients, serratus anterior resulted to be the most reliable and reproducible muscle for measuring the extent of myocardial edema.
我们研究的目的是确定各种骨骼肌作为参考区域的适用性，用于通过T2加权图像对心肌水肿范围进行半自动定量计算T2信号强度（SI）比值。
纳入34例急性心肌梗死（MI）患者。采用4种不同肌肉作为参考，通过T2 SI比值图确定心肌水肿范围：胸大肌和胸小肌、前锯肌、小圆肌-冈下肌和肩胛下肌。将视觉量化的心肌水肿大小作为真值标准。对照组由15例慢性MI患者组成。评估观察者内和观察者间的变异性。
由于图像质量差，4例患者被排除在分析之外。在急性MI患者中，前锯肌与视觉分析的相关性最强（r = 0.799；P < 0.001），观察者内和观察者间变异性低，而其他肌肉导致观察者间变异性显著。相比之下，使用其他肌肉作为参考会导致水肿大小高估。
在急性MI患者中，前锯肌是测量心肌水肿范围最可靠且可重复的肌肉。
