Dombrovskiĭ A M, Miliutina L N
Antibiot Khimioter. 1989 Oct;34(10):774-9.
A total of 2329 Enterobacteriaceae strains in bacterial associations isolated from healthy children and children with salmonellosis were tested for their resistance to antimicrobial drugs. It was shown that the aerobic microbial associations isolated from the healthy children contained higher numbers of strains sensitive or resistant to 1-3 antibiotics while the microbial associations from the children patients with salmonellosis treated with antibiotics contained higher numbers of strains resistant to 6-8 antibiotics. Resistance of the aerobic bacterial associations was mainly defined by resistance of E. coli and K. pneumoniae. The feces of the healthy children never treated with antimicrobial drugs contained strains resistant to them. The use of the antibiotics in the treatment led to increasing numbers of the resistant bacteria and changing species composition of the bacterial associations.
对从健康儿童和沙门氏菌病患儿分离出的细菌联合体中的总共2329株肠杆菌科菌株进行了抗菌药物耐药性检测。结果表明，从健康儿童分离出的需氧微生物联合体中，对1 - 3种抗生素敏感或耐药的菌株数量较多，而用抗生素治疗的沙门氏菌病患儿的微生物联合体中，对6 - 8种抗生素耐药的菌株数量较多。需氧细菌联合体的耐药性主要由大肠杆菌和肺炎克雷伯菌的耐药性决定。从未接受过抗菌药物治疗的健康儿童粪便中含有对这些药物耐药的菌株。治疗中使用抗生素导致耐药菌数量增加，细菌联合体的物种组成发生变化。
