Boudewyns Vanessa, O'Donoghue Amie C, Kelly Bridget, West Suzanne L, Oguntimein Oluwamurewa, Bann Carla M, McCormack Lauren A
RTI International, Research Triangle Park, NC, United States.
Center for Drug Evaluation and Research, FDA, Silver Spring, MD, United States.
Patient Educ Couns. 2015 Jul 10. doi: 10.1016/j.pec.2015.07.003.
To examine patients' comprehension and application of alternative versions of patient medication information handouts for a fictitious drug, and whether patient characteristics influence patients' ability to understand the handouts.
A web-based experiment was conducted in which 1397 adults with rheumatoid arthritis, ankylosing spondylitis, or plaque psoriasis were randomly assigned to one of three conditions: (1) a one-page "Bubbles" format; (2) a one-page "Over-The-Counter" (OTC) format; and (3) a four-page document modeled after MedGuides used in 2009 which served as the control arm. Comprehension and application of information in the handouts were the key outcomes of interest.
Participants who viewed either the Bubbles or OTC formats had greater comprehension than participants who viewed the MedGuide, but did not have better application scores. No significant differences were noted between the Bubbles and OTC formats. Patient characteristics did not moderate the results.
Both formats resulted in better comprehension than the MedGuide format used in the study.
Results provide valuable information on how to design patient information to improve patients' understanding of the risks and benefits of the drugs they are prescribed. Results could be extended to inform the content of other types of patient education materials.
研究患者对一种虚构药物的不同版本患者用药信息手册的理解和应用情况，以及患者特征是否会影响患者对手册的理解能力。
开展了一项基于网络的实验，将1397名患有类风湿性关节炎、强直性脊柱炎或斑块状银屑病的成年人随机分配到三种情况之一：（1）单页“气泡”格式；（2）单页“非处方药”（OTC）格式；（3）以2009年使用的MedGuides为蓝本的四页文档，作为对照组。手册中信息的理解和应用是主要关注的结果。
查看气泡格式或OTC格式的参与者比查看MedGuide的参与者有更好的理解，但应用得分没有更高。气泡格式和OTC格式之间没有显著差异。患者特征并未影响结果。
两种格式都比研究中使用的MedGuide格式带来更好的理解。
研究结果为如何设计患者信息以提高患者对所开药物风险和益处的理解提供了有价值的信息。结果可推广应用于其他类型患者教育材料的内容。
