Jassil Friedrich C, Manning Sean, Lewis Neville, Steinmo Siri, Kingett Helen, Lough Fiona, Pucci Andrea B F, Cheung W H, Finer Nicholas, Walker Judith, Doyle Jaqueline, Batterham Rachel L
Centre for Obesity Research, Rayne Institute, Department of Medicine, University College London, London WC1E 6JJ, UK.
Centre for Obesity Research, Rayne Institute, Department of Medicine, University College London, London WC1E 6JJ, UK ; UCLH Centre for Weight Loss, Metabolic and Endocrine Surgery, University College London Hospitals, Ground Floor West Wing, 250 Euston Road, London NW1 2PG, UK.
J Obes. 2015;2015:693829. doi: 10.1155/2015/693829. Epub 2015 Jun 23.
Lifestyle intervention programs after bariatric surgery have been suggested to maximise health outcomes. This pilot study aimed to investigate the feasibility and impact of an 8-week combined supervised exercise with nutritional-behavioral intervention following Roux-en-Y gastric bypass and sleeve gastrectomy.
Eight female patients (44 ± 8 years old, BMI = 38.5 ± 7.2 kg m(-2)) completed the program. Before and after intervention, anthropometric measures, six-minute walk test (6MWT), physical activity level, eating behavior, and quality of life (QoL) were assessed. Percentage weight loss (%WL) outcomes were compared with a historical matched control group.
The program significantly improved functional capacity (mean increment in 6MWT was 127 ± 107 meters, p = 0.043), increased strenuous intensity exercise (44 ± 49 min/week, p = 0.043), increased consumption of fruits and vegetables (p = 0.034), reduced consumption of ready meals (p = 0.034), and improved "Change in Health" in QoL domain (p = 0.039). The intervention group exhibited greater %WL in the 3-12-month postsurgery period compared to historical controls, 12.2 ± 7.5% versus 5.1 ± 5.4%, respectively (p = 0.027).
Lifestyle intervention program following bariatric surgery is feasible and resulted in several beneficial outcomes. A large randomised control trial is now warranted.
有建议称，减肥手术后进行生活方式干预计划可使健康结果最大化。这项试点研究旨在调查在Roux-en-Y胃旁路手术和袖状胃切除术后进行为期8周的联合监督运动与营养行为干预的可行性和影响。
8名女性患者（44±8岁，体重指数=38.5±7.2kg/m²）完成了该计划。在干预前后，评估了人体测量指标、六分钟步行试验（6MWT）、身体活动水平、饮食行为和生活质量（QoL）。将体重减轻百分比（%WL）结果与历史匹配对照组进行比较。
该计划显著改善了功能能力（6MWT的平均增加量为127±107米，p=0.043），增加了剧烈强度运动（44±49分钟/周，p=0.043），增加了水果和蔬菜的摄入量（p=0.034），减少了即食食品的摄入量（p=0.034），并改善了生活质量领域的“健康变化”（p=0.039）。与历史对照组相比，干预组在术后3至12个月期间的%WL更高，分别为12.2±7.5%和5.1±5.4%（p=0.027）。
减肥手术后的生活方式干预计划是可行的，并产生了一些有益的结果。现在有必要进行一项大型随机对照试验。
