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17岁肾衰竭男孩,肌酐水平创儿科文献报道最高纪录。

17-Year-Old Boy with Renal Failure and the Highest Reported Creatinine in Pediatric Literature.

作者信息

Master Sankar Raj Vimal, Garcia Jessica, Gordillo Roberto

机构信息

Department of Pediatric Nephrology, University of Illinois College of Medicine at Peoria (UICOMP), Peoria, IL 61603, USA.

Department of Pediatrics, University of Illinois College of Medicine at Peoria (UICOMP), Peoria, IL 61603, USA.

出版信息

Case Rep Pediatr. 2015;2015:703960. doi: 10.1155/2015/703960. Epub 2015 Jun 14.

Abstract

The prevalence of chronic kidney disease (CKD) is on the rise and constitutes a major health burden across the world. Clinical presentations in early CKD are usually subtle. Awareness of the risk factors for CKD is important for early diagnosis and treatment to slow the progression of disease. We present a case report of a 17-year-old African American male who presented in a life threatening hypertensive emergency with renal failure and the highest reported serum creatinine in a pediatric patient. A brief discussion on CKD criteria, complications, and potential red flags for screening strategies is provided.

摘要

慢性肾脏病(CKD)的患病率正在上升,成为全球主要的健康负担。CKD早期的临床表现通常不明显。了解CKD的危险因素对于早期诊断和治疗以减缓疾病进展很重要。我们报告一例17岁非裔美国男性病例,该患者因肾衰竭出现危及生命的高血压急症,其血清肌酐水平在儿科患者中报道为最高。本文还简要讨论了CKD的诊断标准、并发症以及筛查策略的潜在警示信号。

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本文引用的文献

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Chronic kidney disease in children and adolescents.儿童和青少年慢性肾脏病
Pediatr Rev. 2014 Jan;35(1):16-29. doi: 10.1542/pir.35-1-16.
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Nutrition in infants and very young children with chronic kidney disease.婴幼儿慢性肾脏病的营养问题。
Pediatr Nephrol. 2012 Sep;27(9):1427-39. doi: 10.1007/s00467-011-1983-x. Epub 2011 Aug 28.
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Insights from the Chronic Kidney Disease in Children (CKiD) study.从儿童慢性肾脏病(CKiD)研究中得到的启示。
Clin J Am Soc Nephrol. 2011 Aug;6(8):2047-53. doi: 10.2215/CJN.10751210. Epub 2011 Jul 22.
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Prevalence of chronic kidney disease in the United States.美国慢性肾脏病的患病率。
JAMA. 2007 Nov 7;298(17):2038-47. doi: 10.1001/jama.298.17.2038.
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Chronic kidney disease in children: the global perspective.儿童慢性肾脏病:全球视角
Pediatr Nephrol. 2007 Dec;22(12):1999-2009. doi: 10.1007/s00467-006-0410-1. Epub 2007 Feb 20.

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